Protein: GRB7
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)

Gene: GRB7
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q14451

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007173 - epidermal growth factor receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

410843

ERBB2
Receptor tyrosine-protein kinase erbB-2

7

20

Small-scale

0.965

High

1050995

FAK1
Focal adhesion kinase 1

4

20

Small-scale

0.912

High

641598

ERBB3
Receptor tyrosine-protein kinase erbB-3

4

20

Small-scale

0.902

High

532081

KIT
Mast/stem cell growth factor receptor Kit

3

20

Small-scale

0.849

High

472060

MET
Hepatocyte growth factor receptor

2

20

Small-scale

0.789

High

1126603

GRB7
Growth factor receptor-bound protein 7

2

20

Small-scale

0.789

High

1126636

STAC3
SH3 and cysteine-rich domain-containing protein 3

2

20

High-throughput

0.783

High

1126658

PICK1
PRKCA-binding protein

2

2

High-throughput

0.783

High

363288

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.768

High

484141

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.757

High

932033

EPHB1
Ephrin type-B receptor 1

1

20

Small-scale

0.740

High

1126630

RND1
Rho-related GTP-binding protein Rho6

1

20

Small-scale

0.740

High

1126657

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.740

High

711352

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.724

High

1126621

LAX1
Lymphocyte transmembrane adapter 1

4

1

High-throughput

0.698

High

463962

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.692

High

439731

INSR
Insulin receptor

1

20

Small-scale

0.680

High

1126624

KCTD6
BTB/POZ domain-containing protein KCTD6

3

13

High-throughput

0.675

High

156630

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.656

High

343528

CPNE6
Copine-6

1

5

High-throughput

0.656

High

1047815

TLE1
Transducin-like enhancer protein 1

1

10

High-throughput

0.656

High

1126610

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

984765

RL31
Large ribosomal subunit protein eL31

3

1

Small-scale

0.633

High

1126673

NOC2L
Nucleolar complex protein 2 homolog

3

2

Small-scale

0.633

High

839272

MTOR
Serine/threonine-protein kinase mTOR

1

5

Small-scale

0.618

High

919961

PLK1
Serine/threonine-protein kinase PLK1

1

16

Small-scale

0.618

High

1126622

RPTOR
Regulatory-associated protein of mTOR

1

5

Small-scale

0.618

High

1126653

RGAP1
Rac GTPase-activating protein 1

1

20

Small-scale

0.618

High

1126663

COR1C
Coronin-1C

1

9

Small-scale

0.618

High

1126674

TBL2
Transducin beta-like protein 2

1

8

Small-scale

0.618

High

220084

TGM5
Protein-glutamine gamma-glutamyltransferase 5

2

3

High-throughput

0.606

High

1126669

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

20

High-throughput

0.587

High

345812

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

5

Small-scale

0.584

High

1126626

OLIG1
Oligodendrocyte transcription factor 1

2

4

High-throughput

0.579

High

1126614

LY66F
Lymphocyte antigen 6 complex locus protein G6f

1

1

Small-scale

0.578

High

161812

RIOK3
Serine/threonine-protein kinase RIO3

2

1

High-throughput

0.571

High

256296

RT14
Small ribosomal subunit protein uS14m

2

1

High-throughput

0.571

High

611864

RL35A
Large ribosomal subunit protein eL33

2

1

High-throughput

0.571

High

693738

RL10
Large ribosomal subunit protein uL16

2

7

High-throughput

0.571

High

716862

RL12
Large ribosomal subunit protein uL11

2

1

High-throughput

0.571

High

785165

RL4
Large ribosomal subunit protein uL4

2

1

High-throughput

0.571

High

960723

RL15
Large ribosomal subunit protein eL15

2

1

High-throughput

0.571

High

961287

RL27
Large ribosomal subunit protein eL27

2

2

High-throughput

0.571

High

978526

RL23A
Large ribosomal subunit protein uL23

2

1

High-throughput

0.571

High

984627

RL39
Large ribosomal subunit protein eL39

2

2

High-throughput

0.571

High

1011793

RT05
Small ribosomal subunit protein uS5m

2

2

High-throughput

0.571

High

1057742

RL18
Large ribosomal subunit protein eL18

2

1

High-throughput

0.571

High

1126620

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

1

High-throughput

0.571

High

1126627

BRX1
Ribosome biogenesis protein BRX1 homolog

2

2

High-throughput

0.571

High

1126635

RL10L
Ribosomal protein uL16-like

2

7

High-throughput

0.571

High

1126639

PURB
Transcriptional regulator protein Pur-beta

2

3

High-throughput

0.571

High

1126648

RIOK2
Serine/threonine-protein kinase RIO2

2

1

High-throughput

0.571

High

1126649

RT26
Small ribosomal subunit protein mS26

2

1

High-throughput

0.571

High

1126671

RT07
Small ribosomal subunit protein uS7m

2

2

High-throughput

0.571

High

288409

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

11

High-throughput

0.553

High

1126632

TRI43
Tripartite motif-containing protein 43

2

13

High-throughput

0.553

High

301049

RL1D1
Ribosomal L1 domain-containing protein 1

2

0

High-throughput

0.547

High

824143

RL13A
Large ribosomal subunit protein uL13

2

0

High-throughput

0.547

High

842370

RL35
Large ribosomal subunit protein uL29

2

0

High-throughput

0.547

High

898650

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.547

High

961726

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.547

High

983654

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.547

High

985463

RL32
Large ribosomal subunit protein eL32

2

0

High-throughput

0.547

High

1011604

RT35
Small ribosomal subunit protein mS35

2

0

High-throughput

0.547

High

1012408

RT21
Small ribosomal subunit protein bS21m

2

0

High-throughput

0.547

High

1016007

RL19
Large ribosomal subunit protein eL19

2

0

High-throughput

0.547

High

1039214

RL6
Large ribosomal subunit protein eL6

2

0

High-throughput

0.547

High

1126618

RIOX2
Ribosomal oxygenase 2

2

0

High-throughput

0.547

High

1126623

RP25L
Ribonuclease P protein subunit p25-like protein

2

0

High-throughput

0.547

High

1126633

RT24
Small ribosomal subunit protein uS3m

2

0

High-throughput

0.547

High

1126645

MMTA2
Multiple myeloma tumor-associated protein 2

2

0

High-throughput

0.547

High

1126655

RPF2
Ribosome production factor 2 homolog

2

0

High-throughput

0.547

High

520040

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

1011448

RT10
Small ribosomal subunit protein uS10m

2

2

High-throughput

0.521

High

1126668

L10K
Leydig cell tumor 10 kDa protein homolog

2

1

High-throughput

0.521

High

1126672

RT02
Small ribosomal subunit protein uS2m

2

3

High-throughput

0.521

High

730584

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

2801

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

12

High-throughput

0.515

High

387833

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.508

High

407002

A1BG
Alpha-1B-glycoprotein

1

20

High-throughput

0.508

High

443789

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

6

High-throughput

0.508

High

573100

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.508

High

586696

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.508

High

935863

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.508

High

984113

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.508

High

1051371

ZBT16
Zinc finger and BTB domain-containing protein 16

1

2

High-throughput

0.508

High

1126637

DOCK7
Dedicator of cytokinesis protein 7

1

13

High-throughput

0.508

High

1126656

PHAX
Phosphorylated adapter RNA export protein

1

1

High-throughput

0.508

High

974932

TYB4
Thymosin beta-4

1

0

High-throughput

0.486

High

1126625

FAD1
FAD synthase

1

0

High-throughput

0.486

High

155665

FCHO1
F-BAR domain only protein 1

1

12

High-throughput

0.481

High

281322

GGYF1
GRB10-interacting GYF protein 1

1

11

Small-scale

0.481

High

1126616

GGYF2
GRB10-interacting GYF protein 2

1

20

Small-scale

0.481

High

172104

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

20

Small-scale

0.479

High

207535

DHX15
ATP-dependent RNA helicase DHX15

1

3

Small-scale

0.479

High

223036

PRC1
Protein regulator of cytokinesis 1

1

11

Small-scale

0.479

High

289535

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

11

Small-scale

0.479

High

330450

LC7L3
Luc7-like protein 3

1

3

Small-scale

0.479

High

344688

AP2A1
AP-2 complex subunit alpha-1

1

8

Small-scale

0.479

High

428143

RLA1
Large ribosomal subunit protein P1

1

2

Small-scale

0.479

High

447014

NPM
Nucleophosmin

1

6

Small-scale

0.479

High

537157

HSP7C
Heat shock cognate 71 kDa protein

1

18

Small-scale

0.479

High

542017

TOP1
DNA topoisomerase 1

1

1

Small-scale

0.479

High

596100

H12
Histone H1.2

1

5

Small-scale

0.479

High

660628

IF4B
Eukaryotic translation initiation factor 4B

1

10

Small-scale

0.479

High

687409

PTBP1
Polypyrimidine tract-binding protein 1

1

7

Small-scale

0.479

High

786601

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

15

Small-scale

0.479

High

788655

SRP14
Signal recognition particle 14 kDa protein

1

1

Small-scale

0.479

High

834445

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

3

Small-scale

0.479

High

855074

NOP2
28S rRNA

1

1

Small-scale

0.479

High

890478

RBP2
E3 SUMO-protein ligase RanBP2

1

9

Small-scale

0.479

High

910511

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

5

Small-scale

0.479

High

913323

MSH6
DNA mismatch repair protein Msh6

1

2

Small-scale

0.479

High

926470

SYRC
Arginine--tRNA ligase, cytoplasmic

1

2

Small-scale

0.479

High

1023059

RBM10
RNA-binding protein 10

1

7

Small-scale

0.479

High

1035614

KIF23
Kinesin-like protein KIF23

1

9

Small-scale

0.479

High

1058413

CKAP4
Cytoskeleton-associated protein 4

1

14

Small-scale

0.479

High

1085982

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

Small-scale

0.479

High

1094174

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.479

High

1099342

SRSF6
Serine/arginine-rich splicing factor 6

1

14

Small-scale

0.479

High

1116649

RIN1
Ras and Rab interactor 1

1

20

Small-scale

0.479

High

1120151

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

1126400

CAPR1
Caprin-1

1

14

Small-scale

0.479

High

1126604

FAT1
Protocadherin Fat 1

1

9

Small-scale

0.479

High

1126605

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

13

Small-scale

0.479

High

1126606

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

7

Small-scale

0.479

High

1126607

NUMA1
Nuclear mitotic apparatus protein 1

1

14

Small-scale

0.479

High

1126613

RRP12
RRP12-like protein

1

1

Small-scale

0.479

High

1126617

LYRIC
Protein LYRIC

1

1

Small-scale

0.479

High

1126628

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

3

Small-scale

0.479

High

1126631

HDAC2
Histone deacetylase 2

1

11

Small-scale

0.479

High

1126634

LTV1
Protein LTV1 homolog

1

2

Small-scale

0.479

High

1126638

RBM14
RNA-binding protein 14

1

13

Small-scale

0.479

High

1126642

TCPH
T-complex protein 1 subunit eta

1

20

Small-scale

0.479

High

1126644

MBB1A
Myb-binding protein 1A

1

1

Small-scale

0.479

High

1126646

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

9

Small-scale

0.479

High

1126647

GNL3
Guanine nucleotide-binding protein-like 3

1

2

Small-scale

0.479

High

1126650

GTPB4
GTP-binding protein 4

1

5

Small-scale

0.479

High

1126651

DDX24
ATP-dependent RNA helicase DDX24

1

13

Small-scale

0.479

High

1126652

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.479

High

1126659

ABCF2
ATP-binding cassette sub-family F member 2

1

1

Small-scale

0.479

High

1126660

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1126661

PUF60
Poly(U)-binding-splicing factor PUF60

1

8

Small-scale

0.479

High

1126662

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

Small-scale

0.479

High

1126664

TPX2
Targeting protein for Xklp2

1

5

Small-scale

0.479

High

1126667

G3BP2
Ras GTPase-activating protein-binding protein 2

1

10

Small-scale

0.479

High

1126670

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

2

Small-scale

0.479

High

1126675

TNPO3
Transportin-3

1

7

Small-scale

0.479

High

846607

MSH2
DNA mismatch repair protein Msh2

1

1

High-throughput

0.464

High

1126609

SETB1
Histone-lysine N-methyltransferase SETDB1

1

7

High-throughput

0.464

High

1126665

KMT2B
Histone-lysine N-methyltransferase 2B

1

12

High-throughput

0.464

High

210942

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

Small-scale

0.458

High

417429

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.458

High

944471

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

1126608

CND1
Condensin complex subunit 1

1

0

Small-scale

0.458

High

1126640

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

Small-scale

0.458

High

1126643

TCF25
Ribosome quality control complex subunit TCF25

1

0

Small-scale

0.458

High

251305

NEMF
Ribosome quality control complex subunit NEMF

1

4

High-throughput

0.445

High

769723

RFC4
Replication factor C subunit 4

1

1

Small-scale

0.437

High

769993

RFC1
Replication factor C subunit 1

1

2

Small-scale

0.437

High

1038860

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

1

Small-scale

0.437

High

1126611

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.437

High

1126615

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

Small-scale

0.437

High

1126666

PRP19
Pre-mRNA-processing factor 19

1

4

Small-scale

0.437

High

1126612

R39L5
Putative ribosomal protein eL39-like 5

1

2

High-throughput

0.407

High

1126619

CRERF
CREB3 regulatory factor

2

0

High-throughput

0.316

High

1126641

HTF4
Transcription factor 12

2

0

High-throughput

0.316

High

1126654

F124B
Protein FAM124B

2

0

High-throughput

0.316

High

211642

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.310

High

1012497

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.298

High

1126629

RT27
Small ribosomal subunit protein mS27

2

0

High-throughput

0.298

High

539174

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

124342

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.264

Low

724070

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025