HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: EIF2A (Q9BY44)
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]
Gene: EIF2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 585
+	Hs
		1114207 TBB8_HUMAN (1-427): 0: 702: 89.70		TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60
+	Hs
		1037374 TBB3_HUMAN (1-444): 0: 712: 92.57		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		792969 TBB4B_HUMAN (1-427): 0: 707: 98.36		LIS1_HUMAN (310-529): 2.68e-16: 83.3: 13.51
+	Hs
		903201 TBB3_HUMAN (1-444): 0: 712: 92.57		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		428404 TBB5_HUMAN (1-429): 0: 709: 100.00		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		933952 TBB4B_HUMAN (1-427): 0: 707: 98.36		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		428123 TBB5_HUMAN (1-429): 0: 709: 100.00		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		903115 TBB4B_HUMAN (1-427): 0: 707: 98.36		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		1046564 TBB2A_HUMAN (1-430): 0: 704: 96.98		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		1312794 TBB6_HUMAN (1-432): 0: 703: 92.13		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		1114214 TBB8_HUMAN (1-427): 0: 702: 89.70		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		381288 TBB4A_HUMAN (1-427): 0: 702: 97.42		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		903481 TBB6_HUMAN (1-432): 0: 703: 92.13		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		428163 TBB5_HUMAN (1-429): 0: 709: 100.00		TBL3_HUMAN (273-459): 4.7e-12: 71: 8.67
+	Hs
		381159 TBB4A_HUMAN (1-427): 0: 702: 97.42		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		1114123 TBB8_HUMAN (1-427): 0: 702: 89.70		WDR5B_HUMAN (282-449): 2.09e-13: 73.7: 13.22