Interactor 1: TRY2 (P07478)
Trypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II)
Gene: PRSS2

Interactor 2: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~Trypsin
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 247
Hs

1 986
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Last updated: 15 Jul 2024