Interactor 1: ADRB2 (P07550)
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Gene: ADRB2

Interactor 2: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 27226565, 28388416, 24561123, 17148612, 23208550, 24658140
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, proximity labelling technology, beta galactosidase complementation, anti tag coimmunoprecipitation, ubiquitin reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 413
Hs

1 409
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024