Protein: MRT4
mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4)

Gene: MRT4, MRTO4
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9UKD2

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

373450

MYC
Myc proto-oncogene protein

4

3

High-throughput

0.676

High

1419729

GTPB4
GTP-binding protein 4

3

7

High-throughput

0.667

High

887315

CEBPA
CCAAT/enhancer-binding protein alpha

3

1

Small-scale

0.631

High

596412

H12
Histone H1.2

2

4

High-throughput

0.628

High

1434933

CCD86
Coiled-coil domain-containing protein 86

3

0

High-throughput

0.622

High

1138738

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.618

High

274800

DNJB6
DnaJ homolog subfamily B member 6

2

1

High-throughput

0.614

High

338209

NSA2
Ribosome biogenesis protein NSA2 homolog

2

2

High-throughput

0.611

High

1008931

RED1
Double-stranded RNA-specific editase 1

2

6

High-throughput

0.611

High

1114618

CUL3
Cullin-3

2

6

High-throughput

0.611

High

1161747

IF16
Gamma-interferon-inducible protein 16

2

3

High-throughput

0.611

High

1331476

ZFP41
Zinc finger protein 41 homolog

3

3

High-throughput

0.609

High

425673

ISG15
Ubiquitin-like protein ISG15

2

2

Small-scale

0.595

High

129533

MEN1
Menin

2

1

High-throughput

0.584

High

364005

EGFR
Epidermal growth factor receptor

2

3

High-throughput

0.584

High

1397757

MAGBA
Melanoma-associated antigen B10

2

3

High-throughput

0.574

High

401677

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.571

High

1452469

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

141162

NOP56
Nucleolar protein 56

1

2

High-throughput

0.536

High

443553

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.536

High

624172

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

4

High-throughput

0.536

High

694059

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

697686

PYR1
Multifunctional protein CAD

1

2

High-throughput

0.536

High

833222

MNDA
Myeloid cell nuclear differentiation antigen

1

3

High-throughput

0.536

High

854378

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

908476

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.536

High

961883

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.536

High

1006785

SRPK2
SRSF protein kinase 2

1

10

High-throughput

0.536

High

1027837

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

1038486

TIE2
Angiopoietin-1 receptor

1

4

High-throughput

0.536

High

1113019

CUL2
Cullin-2

1

6

High-throughput

0.536

High

1288290

LYRIC
Protein LYRIC

1

1

High-throughput

0.536

High

1291269

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1368248

CDKL2
Cyclin-dependent kinase-like 2

1

3

High-throughput

0.536

High

1402633

SRPK1
SRSF protein kinase 1

1

8

High-throughput

0.536

High

1433390

PLK3
Serine/threonine-protein kinase PLK3

1

1

High-throughput

0.536

High

1461038

SRPK3
SRSF protein kinase 3

1

7

High-throughput

0.536

High

1461039

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.536

High

1447417

ANLN
Anillin

2

1

High-throughput

0.533

High

765982

BMI1
Polycomb complex protein BMI-1

2

5

High-throughput

0.521

High

641280

FGFR2
Fibroblast growth factor receptor 2

1

7

High-throughput

0.500

High

389559

FINC
Fibronectin

1

1

High-throughput

0.489

High

902303

RB27A
Ras-related protein Rab-27A

1

1

High-throughput

0.489

High

1446894

TF7L2
Transcription factor 7-like 2

1

4

High-throughput

0.489

High

1453894

H2AW
Core histone macro-H2A.2

1

7

High-throughput

0.489

High

139633

PESC
Pescadillo homolog

1

2

Small-scale

0.479

High

173532

XPO1
Exportin-1

1

3

Small-scale

0.479

High

240012

SOX15
Transcription factor SOX-15

1

4

High-throughput

0.479

High

248368

HBP1
HMG box-containing protein 1

1

6

High-throughput

0.479

High

272539

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.479

High

320132

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

331402

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

346472

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

406778

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

473167

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.479

High

520644

RARA
Retinoic acid receptor alpha

1

5

Small-scale

0.479

High

620641

NUCL
Nucleolin

1

1

High-throughput

0.479

High

714506

PML
Protein PML

1

4

Small-scale

0.479

High

761307

RYK
Tyrosine-protein kinase RYK

1

6

High-throughput

0.479

High

762067

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

777789

VGFR3
Vascular endothelial growth factor receptor 3

1

4

High-throughput

0.479

High

831624

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

872869

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

900215

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.479

High

978780

RL23A
Large ribosomal subunit protein uL23

1

3

Small-scale

0.479

High

979338

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.479

High

1024917

VIGLN
Vigilin

1

2

High-throughput

0.479

High

1034202

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

7

High-throughput

0.479

High

1035980

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.479

High

1067821

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

1087614

GRSF1
G-rich sequence factor 1

1

5

High-throughput

0.479

High

1088231

MERTK
Tyrosine-protein kinase Mer

1

7

High-throughput

0.479

High

1088610

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

1107320

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1137192

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

3

High-throughput

0.479

High

1141012

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1197745

MIDN
Midnolin

1

1

High-throughput

0.479

High

1207460

HABP4
Intracellular hyaluronan-binding protein 4

1

2

High-throughput

0.479

High

1215887

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1235565

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

1238501

ZN746
Zinc finger protein 746

1

2

High-throughput

0.479

High

1256028

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1290804

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

1335058

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1361256

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

1368668

KAT6A
Histone acetyltransferase KAT6A

1

6

High-throughput

0.479

High

1372479

TP4A1
Protein tyrosine phosphatase type IVA 1

1

2

High-throughput

0.479

High

1380242

FBXW7
F-box/WD repeat-containing protein 7

1

8

High-throughput

0.479

High

1387043

NMD3
60S ribosomal export protein NMD3

1

2

Small-scale

0.479

High

1393813

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1402338

RANB9
Ran-binding protein 9

1

2

High-throughput

0.479

High

1404827

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.479

High

1405746

KLF6
Krueppel-like factor 6

1

5

High-throughput

0.479

High

1434192

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1436543

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

1437783

XPO5
Exportin-5

1

3

Small-scale

0.479

High

1438076

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

1448237

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.479

High

1454351

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1459253

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1459728

RLP24
Probable ribosome biogenesis protein RLP24

1

7

Small-scale

0.479

High

1461041

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.479

High

226616

TLX2
T-cell leukemia homeobox protein 2

1

0

High-throughput

0.458

High

248133

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

1112427

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

1

0

High-throughput

0.458

High

1156894

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1330973

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1352821

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

354799

PAK4
Serine/threonine-protein kinase PAK 4

1

1

High-throughput

0.445

High

1032883

XPC
DNA repair protein complementing XP-C cells

1

1

High-throughput

0.445

High

1130514

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1209777

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

170417

AURKA
Aurora kinase A

1

3

High-throughput

0.437

High

411107

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

2

High-throughput

0.437

High

589996

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

610065

VGFR1
Vascular endothelial growth factor receptor 1

1

4

High-throughput

0.437

High

640324

EPHA1
Ephrin type-A receptor 1

1

3

High-throughput

0.437

High

650478

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.437

High

680757

CATS
Cathepsin S

1

1

High-throughput

0.437

High

696823

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720359

UFO
Tyrosine-protein kinase receptor UFO

1

6

High-throughput

0.437

High

769476

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

787099

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

4

High-throughput

0.437

High

879602

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

937962

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.437

High

962617

RHOA
Transforming protein RhoA

1

3

High-throughput

0.437

High

971266

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

978390

RHOB
Rho-related GTP-binding protein RhoB

1

3

High-throughput

0.437

High

1118694

KLF9
Krueppel-like factor 9

1

5

High-throughput

0.437

High

1251978

LMTK1
Serine/threonine-protein kinase LMTK1

1

5

High-throughput

0.437

High

1276940

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1328998

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

4

High-throughput

0.437

High

1367548

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1385908

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

1418507

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1433570

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.437

High

1436821

WDR76
WD repeat-containing protein 76

1

8

High-throughput

0.437

High

1438232

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.437

High

1460381

KLF15
Krueppel-like factor 15

1

4

High-throughput

0.437

High

1461037

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

1461040

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

619949

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.407

High

965317

WDR5
WD repeat-containing protein 5

1

9

High-throughput

0.407

High

1398019

MF14A
Hippocampus abundant transcript 1 protein

1

1

High-throughput

0.407

High

1143108

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.298

High

180100

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

488887

FURIN
Furin

1

0

High-throughput

0.249

Low

693127

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

895815

LHX2
LIM/homeobox protein Lhx2

1

0

High-throughput

0.249

Low

976647

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

1327259

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

944373

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.232

Low

1401903

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025