HitPredict

Interactor 1: SEC4 (P07560)
Ras-related protein SEC4 (Suppressor of RHO3 protein 6)
Gene: SEC4

Interactor 2: SED5 (Q01590)
Integral membrane protein SED5
Gene: SED5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	16107716
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006906 - vesicle fusion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 215 Sc			1 340
+	Sc
		350910 YPT1_YEAST (13-215): 2.85e-85: 252: 46.60		SED5_YEAST (1-340): 6.94e-64: 207: 100.00
+	Hs
		914043 RB11A_HUMAN (10-215): 5.54e-82: 244: 39.44		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Sc
		350925 YPT1_YEAST (13-215): 2.85e-85: 252: 46.60		TLG2_YEAST (3-339): 8.21e-45: 159: 13.54
+	Hs
		918901 RAB1A_HUMAN (10-215): 3.47e-83: 247: 49.28		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		914188 RB11A_HUMAN (10-215): 5.54e-82: 244: 39.44		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		178468 RAB1A_HUMAN (10-215): 3.47e-83: 247: 49.28		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Sc
		429249 SEC4_YEAST (1-215): 6.97e-82: 244: 100.00		TLG2_YEAST (3-339): 8.21e-45: 159: 13.54
+	Hs
		178466 RB11A_HUMAN (10-215): 5.54e-82: 244: 39.44		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Mm
		914520 RB11A_MOUSE (10-215): 5.54e-82: 244: 39.44		STX12_MOUSE (78-323): 2.15e-45: 157: 18.22
+	Hs
		1079938 RB11B_HUMAN (10-215): 8.47e-79: 236: 38.14		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		914044 RB11A_HUMAN (10-215): 5.54e-82: 244: 39.44		STX3_HUMAN (90-321): 5.45e-44: 154: 12.39
+	Hs
		178552 RB11B_HUMAN (10-215): 8.47e-79: 236: 38.14		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		894731 RAB8A_HUMAN (13-211): 1.32e-78: 235: 52.00		STX3_HUMAN (90-321): 5.45e-44: 154: 12.39
+	Sc
		350858 YPT1_YEAST (13-215): 2.85e-85: 252: 46.60		PEP12_YEAST (83-320): 2.3e-15: 77.3: 16.60