HitPredict

Interactor 1: RPAC1 (P07703)
DNA-directed RNA polymerases I and III subunit RPAC1 (RNA polymerases I and III subunit AC1) (C37) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (AC40) (C40)
Gene: RPC40

Interactor 2: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 11805826, 11805837, 24307683, 11918799, 16554755, 16429126, 18467557, 37968396, 21048197, 14759368
Identification Methods tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_3, RNA_pol_L~RNA_pol_Rpb1_4, RNA_pol_L~RNA_pol_Rpb1_5
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 335
Sc

1 1664
+ Sc
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Sp
+ Sc
+ Hv
+ Sc
+ Hs
+ Hs
+ Sc
+ At
+ At
+ At
+ At
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024