HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: RHG05 (Q13017)
Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)
Gene: ARHGAP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010634 - positive regulation of epithelial cell migration
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1502
+	Hs
		430350 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG35_HUMAN (1-1479): 0: 1565: 49.43
+	Hs
		430167 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9B_HUMAN (792-1497): 8.58e-114: 400: 15.74
+	Hs
		70642 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9A_HUMAN (956-1445): 1.69e-84: 309: 20.51
+	Hs
		430214 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG21_HUMAN (940-1500): 2.11e-71: 267: 16.43
+	Hs
		430262 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG24_HUMAN (1244-1462): 1.18e-61: 228: 27.75
+	Hs
		430021 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		BCR_HUMAN (1250-1420): 2.54e-20: 100: 31.79
+	Hs
		430224 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG17_HUMAN (1256-1449): 6.44e-20: 98.6: 31.31