HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: RHGBB (Q3KRB8)
Inactive Rho GTPase-activating protein 11B (Rho-type GTPase-activating protein 11B)
Gene: ARHGAP11B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32203420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 267
+	Hs
		430214 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG21_HUMAN (28-267): 1.89e-63: 217: 22.89
+	Hs
		430262 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG24_HUMAN (32-266): 1.06e-64: 216: 23.55
+	Hs
		430224 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG17_HUMAN (10-255): 2.56e-62: 212: 22.00
+	Hs
		70642 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9A_HUMAN (23-255): 4.22e-60: 207: 21.63
+	Hs
		430167 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9B_HUMAN (21-262): 2.94e-59: 205: 22.61
+	Hs
		430021 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		BCR_HUMAN (17-253): 4.47e-59: 204: 25.00
+	Hs
		253303 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SRGP2_HUMAN (59-227): 8.7e-53: 186: 30.11
+	Hs
		430157 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHG05_HUMAN (44-229): 5.62e-52: 183: 27.08