HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0016020 - membrane and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 7388
+	Hs
		430138 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		430182 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		430173 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		714965 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23