Interactor 1: CATB (P07858)
Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
Gene: CTSB

Interactor 2: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 26208400
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005518 - collagen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0008233 - peptidase activity
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 339
Hs

1 707
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024