HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: ROR2 (Q01974)
Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)
Gene: ROR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 943
+	Hs
		431749 HS90A_HUMAN (1-732): 0: 1087: 100.00		ROR1_HUMAN (41-942): 0: 678: 56.94
+	Hs
		169159 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUSK_HUMAN (5-756): 8.41e-178: 539: 24.13
+	Hs
		431472 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR1_HUMAN (18-803): 1.13e-169: 517: 18.90
+	Hs
		169160 HS90B_HUMAN (19-732): 0: 1059: 86.13		MUSK_HUMAN (5-756): 8.41e-178: 539: 24.13
+	Hs
		431536 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR3_HUMAN (34-805): 8.14e-166: 506: 19.04
+	Hs
		431534 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR4_HUMAN (36-796): 2.55e-151: 468: 20.75
+	Hs
		431568 HS90A_HUMAN (1-732): 0: 1087: 100.00		UFO_HUMAN (28-837): 6.67e-148: 462: 19.23
+	Hs
		431435 HS90A_HUMAN (1-732): 0: 1087: 100.00		RET_HUMAN (254-846): 1.68e-140: 449: 21.89
+	Hs
		431788 HS90A_HUMAN (1-732): 0: 1087: 100.00		MERTK_HUMAN (17-898): 2.29e-139: 443: 16.32
+	Hs
		431871 HS90A_HUMAN (1-732): 0: 1087: 100.00		ERBB4_HUMAN (139-924): 3.66e-135: 439: 20.89
+	Hs
		431770 HS90A_HUMAN (1-732): 0: 1087: 100.00		TYRO3_HUMAN (18-839): 5.45e-136: 431: 18.71
+	Hs
		431892 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK3_HUMAN (259-755): 4.11e-127: 406: 28.91
+	Hs
		431848 HS90A_HUMAN (1-732): 0: 1087: 100.00		FAK2_HUMAN (429-864): 6.44e-113: 372: 29.00
+	Hs
		431765 HS90A_HUMAN (1-732): 0: 1087: 100.00		FAK1_HUMAN (358-850): 2.55e-110: 367: 27.18
+	Hs
		431692 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA4_HUMAN (370-779): 6.97e-110: 364: 33.01
+	Hs
		431901 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK2_HUMAN (465-753): 4.36e-111: 363: 44.29
+	Hs
		384111 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK1_HUMAN (478-748): 6.27e-66: 238: 43.91
+	Hs
		431907 HS90A_HUMAN (1-732): 0: 1087: 100.00		DDR2_HUMAN (461-751): 3.3e-55: 208: 38.39
+	Hs
		431691 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB1_HUMAN (466-746): 8.35e-54: 205: 41.40
+	Hs
		431438 HS90A_HUMAN (1-732): 0: 1087: 100.00		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68