HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1121
+	Hs
		438264 HS90B_HUMAN (19-732): 0: 1059: 86.13		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		538272 ENPL_HUMAN (14-701): 0: 898: 46.78		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		431958 HS90A_HUMAN (1-732): 0: 1087: 100.00		NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13
+	Hs
		432052 HS90A_HUMAN (1-732): 0: 1087: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		438638 HS90B_HUMAN (19-732): 0: 1059: 86.13		PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16
+	Hs
		125097 HS90A_HUMAN (1-732): 0: 1087: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		431877 HS90A_HUMAN (1-732): 0: 1087: 100.00		CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69
+	Hs
		438347 HS90B_HUMAN (19-732): 0: 1059: 86.13		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		432265 HS90A_HUMAN (1-732): 0: 1087: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		125101 HS90B_HUMAN (19-732): 0: 1059: 86.13		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		438596 HS90B_HUMAN (19-732): 0: 1059: 86.13		CYH4_HUMAN (95-286): 8.79e-43: 163: 20.98
+	Hs
		438531 HS90B_HUMAN (19-732): 0: 1059: 86.13		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		432252 HS90A_HUMAN (1-732): 0: 1087: 100.00		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Hs
		438516 HS90B_HUMAN (19-732): 0: 1059: 86.13		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Hs
		538313 ENPL_HUMAN (14-701): 0: 898: 46.78		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		538401 ENPL_HUMAN (14-701): 0: 898: 46.78		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Sc
		366333 HSP82_YEAST (16-732): 0: 907: 60.08		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99
+	Sc
		543785 HSC82_YEAST (16-732): 0: 902: 59.39		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99
+	Hs
		538146 ENPL_HUMAN (14-701): 0: 898: 46.78		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17