HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: FXL15 (Q9H469)
F-box/LRR-repeat protein 15 (F-box only protein 37)
Gene: FBXL15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 300
+	Hs
		438527 HS90B_HUMAN (19-732): 0: 1059: 86.13		FXL15_HUMAN (1-300): 3.34e-68: 215: 100.00
+	Hs
		431812 HS90A_HUMAN (1-732): 0: 1087: 100.00		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Hs
		432050 HS90A_HUMAN (1-732): 0: 1087: 100.00		FXL14_HUMAN (29-276): 1.48e-30: 120: 23.55
+	Hs
		432349 HS90A_HUMAN (1-732): 0: 1087: 100.00		FBXL2_HUMAN (5-249): 1.36e-30: 120: 22.05
+	Hs
		432347 HS90A_HUMAN (1-732): 0: 1087: 100.00		FBXL4_HUMAN (17-276): 1.38e-29: 119: 21.40
+	Hs
		438132 HS90B_HUMAN (19-732): 0: 1059: 86.13		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Hs
		438345 HS90B_HUMAN (19-732): 0: 1059: 86.13		FXL14_HUMAN (29-276): 1.48e-30: 120: 23.55
+	Hs
		438607 HS90B_HUMAN (19-732): 0: 1059: 86.13		FBXL2_HUMAN (5-249): 1.36e-30: 120: 22.05
+	Hs
		438605 HS90B_HUMAN (19-732): 0: 1059: 86.13		FBXL4_HUMAN (17-276): 1.38e-29: 119: 21.40
+	Hs
		432071 HS90A_HUMAN (1-732): 0: 1087: 100.00		FXL13_HUMAN (170-285): 1.65e-11: 66.5: 16.38
+	Hs
		438362 HS90B_HUMAN (19-732): 0: 1059: 86.13		FXL13_HUMAN (170-285): 1.65e-11: 66.5: 16.38