HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: AKT2 (P31751)
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC protein kinase beta) (RAC-PK-beta)
Gene: AKT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 481
+	Hs
		420807 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT2_HUMAN (1-481): 0: 589: 100.00
+	Hs
		682181 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT2_HUMAN (1-481): 0: 589: 100.00
+	Mm
		682111 H2B2B_MOUSE (1-126): 1.28e-55: 171: 98.41		AKT1_MOUSE (1-478): 0: 566: 81.84
+	Mm
		682113 H2B1C_MOUSE (1-126): 7.88e-55: 169: 98.41		AKT1_MOUSE (1-478): 0: 566: 81.84
+	Hs
		617926 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		420806 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		681878 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		681686 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		AKT1_HUMAN (1-478): 0: 564: 81.63
+	Hs
		408525 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		408583 H2BFS_HUMAN (1-126): 8.79e-55: 169: 96.03		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		408591 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		408624 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		408666 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		408565 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KPCB_HUMAN (72-478): 5.56e-147: 436: 40.63
+	Hs
		568756 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		KAPCA_HUMAN (141-447): 2.12e-144: 419: 41.69
+	Hs
		617936 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		KS6A3_HUMAN (55-452): 8.73e-107: 335: 23.36
+	Hs
		420815 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		KS6A3_HUMAN (55-452): 8.73e-107: 335: 23.36
+	Hs
		850663 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KS6A3_HUMAN (55-452): 8.73e-107: 335: 23.36
+	Hs
		270420 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KS6A5_HUMAN (60-406): 1.32e-104: 331: 27.25
+	Hs
		270378 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KS6A5_HUMAN (60-406): 1.32e-104: 331: 27.25