HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	35043518, 22268729, 22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006986 - response to unfolded protein
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 293
+	Hs
		438556 HS90B_HUMAN (19-732): 0: 1059: 86.13		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		432146 HS90A_HUMAN (1-732): 0: 1087: 100.00		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83
+	Hs
		432080 HS90A_HUMAN (1-732): 0: 1087: 100.00		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80
+	Hs
		538414 ENPL_HUMAN (14-701): 0: 898: 46.78		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		438372 HS90B_HUMAN (19-732): 0: 1059: 86.13		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80