HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 26167880, 23602568
Identification Methods enzymatic study, affinity chromatography technology, tandem affinity purification, protein kinase assay
Interaction Type direct interaction, physical association, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0000785 - chromatin
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 306
Hs

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Last updated: 15 Jul 2024