Protein: SDA1
Protein SDA1 (Severe depolymerization of actin protein 1)

Gene: SDA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: P53313

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0007089 - traversing start control point of mitotic cell cycle
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

816873

NUG1
Nuclear GTP-binding protein NUG1

9

2

Small-scale

0.748

High

919542

NOG2
Nucleolar GTP-binding protein 2

9

2

Small-scale

0.748

High

670309

NAP1
Nucleosome assembly protein

7

3

Small-scale

0.746

High

919552

NOG1
Nucleolar GTP-binding protein 1

6

1

Small-scale

0.727

High

919553

ARX1
Probable metalloprotease ARX1

11

0

Small-scale

0.724

High

918929

PESC
Pescadillo homolog

11

0

Small-scale

0.720

High

806637

RIX1
Pre-rRNA-processing protein RIX1

8

0

Small-scale

0.715

High

673580

NLE1
Ribosome assembly protein 4

5

1

Small-scale

0.709

High

919543

IPI3
Pre-rRNA-processing protein IPI3

5

2

Small-scale

0.709

High

919560

BUD20
Bud site selection protein 20

5

0

Small-scale

0.688

High

827563

RLP7
Ribosome biogenesis protein RLP7

4

1

Small-scale

0.687

High

919565

MDN1
Midasin

4

1

Small-scale

0.687

High

684797

RL5
Large ribosomal subunit protein uL18

4

1

Small-scale

0.683

High

919566

NOP53
Ribosome biogenesis protein NOP53

5

0

Small-scale

0.669

High

919572

IF6
Eukaryotic translation initiation factor 6

3

1

High-throughput

0.667

High

864176

ALB1
Ribosome biogenesis protein ALB1

4

0

Small-scale

0.664

High

917666

LSG1
Large subunit GTPase 1

3

2

High-throughput

0.662

High

919544

NOP15
Ribosome biogenesis protein 15

3

1

High-throughput

0.662

High

818254

NSA2
Ribosome biogenesis protein NSA2

4

0

Small-scale

0.658

High

432649

RL7A
Large ribosomal subunit protein uL30A

3

1

High-throughput

0.656

High

803895

CIC1
Proteasome-interacting protein CIC1

4

0

Small-scale

0.643

High

570090

RL3
Large ribosomal subunit protein uL3

3

1

Small-scale

0.609

High

805003

IPI1
Pre-rRNA-processing protein IPI1

3

0

Small-scale

0.606

High

782395

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.595

High

433759

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.584

High

750115

MRT4
Ribosome assembly factor MRT4

2

2

Small-scale

0.584

High

531823

RL4A
Large ribosomal subunit protein uL4A

2

1

Small-scale

0.571

High

918038

CGR1
rRNA-processing protein CGR1

2

0

Small-scale

0.559

High

154200

RL36B
Large ribosomal subunit protein eL36B

2

1

High-throughput

0.558

High

712630

RL8B
Large ribosomal subunit protein eL8B

2

1

High-throughput

0.558

High

527281

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

545714

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

511243

RL20B
Large ribosomal subunit protein eL20B

2

1

High-throughput

0.533

High

919568

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

518085

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

381189

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381578

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

419819

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

442029

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

512561

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513539

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

689088

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

689254

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

781232

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.479

High

792163

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

803416

RL14B
Large ribosomal subunit protein eL14B

1

1

High-throughput

0.479

High

918308

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.479

High

919547

H3
Histone H3

1

2

High-throughput

0.479

High

919556

ERB1
Ribosome biogenesis protein ERB1

1

1

High-throughput

0.479

High

919557

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

919559

RLP24
Ribosome biogenesis protein RLP24

1

1

Small-scale

0.479

High

919569

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

919571

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

919573

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.479

High

919574

MEX67
mRNA export factor MEX67

1

1

Small-scale

0.479

High

149876

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382244

H4
Histone H4

1

0

High-throughput

0.458

High

434056

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.458

High

436077

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436475

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

674743

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677947

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

689573

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707754

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735080

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

745096

AFG2
ATPase family gene 2 protein

1

0

High-throughput

0.458

High

758043

MTR2
mRNA transport regulator MTR2

1

0

Small-scale

0.458

High

764128

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

795831

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

804635

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

812518

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

814350

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

826698

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

830148

NOP2
25S rRNA

1

0

High-throughput

0.458

High

844551

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

919545

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

919554

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

919555

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

919561

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

919562

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

919564

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

919567

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

919570

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

524682

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

727208

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

819367

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

885034

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.445

High

409761

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.437

High

432886

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.437

High

433253

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.437

High

434414

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.437

High

434622

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

455177

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

503821

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.437

High

503940

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.437

High

504330

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

601092

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

820927

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.437

High

863856

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.437

High

902656

RL9B
Large ribosomal subunit protein uL6B

1

1

High-throughput

0.437

High

919546

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.437

High

919558

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

919563

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

427382

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.407

High

752555

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

410250

RL25
Large ribosomal subunit protein uL23

3

0

High-throughput

0.342

High

569832

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.318

High

811000

TCPD
T-complex protein 1 subunit delta

2

0

High-throughput

0.307

High

514331

RL12B
Large ribosomal subunit protein uL11B

2

0

High-throughput

0.305

High

433053

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.279

Low

879871

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.279

Low

919549

AP1M1
AP-1 complex subunit mu-1-I

1

0

High-throughput

0.279

Low

673517

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.269

Low

865017

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.269

Low

383812

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

503157

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

511457

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

514749

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

558817

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

649649

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

661754

VPS3
Vacuolar protein sorting-associated protein 3

1

0

Small-scale

0.249

Low

747492

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753495

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

778452

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

792548

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.249

Low

802293

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

825885

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

919548

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

919550

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

919551

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

814906

VPS52
Vacuolar protein sorting-associated protein 52

1

0

High-throughput

0.238

Low

394768

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

453712

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

510686

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025