HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: LAMP1 (P11279)
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)
Gene: LAMP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019899 - enzyme binding GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 417
+	Hs
		506858 SRC_HUMAN (1-543): 0: 601: 74.22		LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00
+	Hs
		433233 YES_HUMAN (1-543): 0: 617: 100.00		LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94
+	Hs
		522736 SRC_HUMAN (1-543): 0: 601: 74.22		LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94
+	Hs
		411972 FYN_HUMAN (1-543): 0: 582: 72.16		LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94
+	Hs
		433542 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00
+	Hs
		433548 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		LAMP2_HUMAN (4-415): 3.06e-170: 484: 34.94
+	Hs
		506944 EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00		LAMP1_HUMAN (1-417): 6.95e-180: 509: 100.00
+	Hs
		433509 YES_HUMAN (1-543): 0: 617: 100.00		LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05
+	Hs
		523214 SRC_HUMAN (1-543): 0: 601: 74.22		LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05
+	Hs
		434087 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		LAMP3_HUMAN (157-417): 2.56e-77: 247: 26.05