Protein: RL17B
Large ribosomal subunit protein uL22B (60S ribosomal protein L17-B) (L20) (YL17)

Gene: RL17B, RPL17B
Organism: Saccharomyces cerevisiae S288C
Interactions: 190
UniProt ID: P46990

Gene Ontology (top 5):
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol
GO:0022625 - cytosolic large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782365

RPF2
Ribosome biogenesis protein RPF2

3

1

Small-scale

0.839

High

524380

HSP71
Heat shock protein SSA1

4

4

High-throughput

0.672

High

415029

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.618

High

433236

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.618

High

531794

RL4A
Large ribosomal subunit protein uL4A

1

5

High-throughput

0.618

High

863847

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.618

High

679824

CDC48
Cell division control protein 48

2

5

High-throughput

0.611

High

863867

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

3

High-throughput

0.611

High

504288

RL31A
Large ribosomal subunit protein eL31A

2

3

High-throughput

0.584

High

689066

RL16A
Large ribosomal subunit protein uL13A

2

5

High-throughput

0.584

High

863851

NSA1
Ribosome biogenesis protein NSA1

2

2

Small-scale

0.584

High

863855

PESC
Pescadillo homolog

2

1

Small-scale

0.584

High

863860

NOG2
Nucleolar GTP-binding protein 2

2

4

High-throughput

0.584

High

863890

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

863876

HMO1
High mobility group protein 1

2

2

High-throughput

0.571

High

863895

MAK21
Ribosome biogenesis protein MAK21

1

4

High-throughput

0.536

High

558785

CAF20
Cap-associated protein CAF20

2

1

Small-scale

0.533

High

863842

URB2
Nucleolar pre-ribosomal-associated protein 2

2

1

Small-scale

0.533

High

707487

TF2B
Transcription initiation factor IIB

2

1

High-throughput

0.521

High

863891

NOP53
Ribosome biogenesis protein NOP53

2

2

Small-scale

0.521

High

701716

URA7
CTP synthase 1

1

1

High-throughput

0.489

High

722049

XPO1
Exportin-1

1

2

High-throughput

0.489

High

824630

YIQ1
Uncharacterized protein YIL161W

1

1

High-throughput

0.489

High

154188

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.479

High

383147

RLA4
Large ribosomal subunit protein P2B

1

3

High-throughput

0.479

High

409749

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

410210

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

427337

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

427582

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.479

High

427713

RLA2
Large ribosomal subunit protein P2A

1

3

High-throughput

0.479

High

432623

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

432867

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.479

High

433716

RL26A
Large ribosomal subunit protein uL24A

1

5

High-throughput

0.479

High

434041

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

434259

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

434396

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

434601

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

482047

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

503931

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

511223

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

511443

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

513521

RL1A
Large ribosomal subunit protein uL1A

1

4

High-throughput

0.479

High

513711

RL2A
Large ribosomal subunit protein uL2A

1

3

High-throughput

0.479

High

514021

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

514309

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

515123

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

515278

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

528836

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

569810

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

570060

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

601075

RL8A
Large ribosomal subunit protein eL8A

1

3

High-throughput

0.479

High

646454

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

663688

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

670873

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

682326

SPB4
ATP-dependent rRNA helicase SPB4

1

7

High-throughput

0.479

High

684768

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

689238

RL16B
Large ribosomal subunit protein uL13B

1

5

High-throughput

0.479

High

712604

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.479

High

727141

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

739402

ZUO1
Zuotin

1

3

High-throughput

0.479

High

750103

MRT4
Ribosome assembly factor MRT4

1

4

High-throughput

0.479

High

781212

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

792535

RL32
Large ribosomal subunit protein eL32

1

2

High-throughput

0.479

High

795646

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

2

High-throughput

0.479

High

796877

GID4
GID complex substrate-recognition subunit 4

1

1

High-throughput

0.479

High

803409

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

804259

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.479

High

806142

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

812436

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

813702

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.479

High

813997

IF2P
Eukaryotic translation initiation factor 5B

1

3

High-throughput

0.479

High

820910

RL13B
Large ribosomal subunit protein eL13B

1

4

High-throughput

0.479

High

825874

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.479

High

827541

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.479

High

830133

NOP2
25S rRNA

1

1

Small-scale

0.479

High

831817

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

835824

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.479

High

850067

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

863845

RL37A
Large ribosomal subunit protein eL37A

1

3

High-throughput

0.479

High

863846

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

863848

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.479

High

863849

RL37B
Large ribosomal subunit protein eL37B

1

3

High-throughput

0.479

High

863852

LSG1
Large subunit GTPase 1

1

4

High-throughput

0.479

High

863853

RL26B
Large ribosomal subunit protein uL24B

1

5

High-throughput

0.479

High

863859

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.479

High

863862

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

High-throughput

0.479

High

863863

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

863866

RL34A
Large ribosomal subunit protein eL34A

1

4

High-throughput

0.479

High

863868

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.479

High

863870

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

863871

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

863872

HAS1
ATP-dependent RNA helicase HAS1

1

10

High-throughput

0.479

High

863873

ARX1
Probable metalloprotease ARX1

1

2

High-throughput

0.479

High

863879

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

863880

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.479

High

863886

ELP1
Elongator complex protein 1

1

1

High-throughput

0.479

High

863888

RIX7
Ribosome biogenesis ATPase RIX7

1

5

High-throughput

0.479

High

863896

RL7B
Large ribosomal subunit protein uL30B

1

6

High-throughput

0.479

High

863898

DBP10
ATP-dependent RNA helicase DBP10

1

9

High-throughput

0.479

High

863900

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

863901

RL13A
Large ribosomal subunit protein eL13A

1

4

High-throughput

0.479

High

863903

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.479

High

515372

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

657103

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

806754

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

815414

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

649640

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.457

High

692388

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.457

High

481666

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.445

High

527031

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

545371

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

618911

ARF2
ADP-ribosylation factor 2

1

1

High-throughput

0.445

High

741857

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

819117

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

402042

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.437

High

438724

SC160
Protein SCP160

1

1

High-throughput

0.437

High

448754

SNF1
Carbon catabolite-derepressing protein kinase

1

1

Small-scale

0.437

High

567692

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

594442

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

637237

PWP1
Periodic tryptophan protein 1

1

5

High-throughput

0.437

High

666492

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

677464

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

678696

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

1

Small-scale

0.437

High

735048

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

744315

CHD1
Chromo domain-containing protein 1

1

4

High-throughput

0.437

High

790264

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

798253

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.437

High

809352

STM1
Suppressor protein STM1

1

1

High-throughput

0.437

High

812069

DHH1
ATP-dependent RNA helicase DHH1

1

7

High-throughput

0.437

High

815309

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

824905

TM108
Protein TMA108

1

2

High-throughput

0.437

High

826616

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

844513

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

849716

OTU1
Ubiquitin thioesterase OTU1

1

2

High-throughput

0.437

High

863843

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

863850

VID30
GID complex subunit 1

1

2

High-throughput

0.437

High

863856

SDA1
Protein SDA1

1

1

High-throughput

0.437

High

863857

H1
Histone H1

1

1

High-throughput

0.437

High

863861

GIS2
Zinc finger protein GIS2

1

5

High-throughput

0.437

High

863864

NST1
Stress response protein NST1

1

1

High-throughput

0.437

High

863865

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

863869

MLP1
Protein MLP1

1

1

High-throughput

0.437

High

863875

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

863878

DHR1
Probable ATP-dependent RNA helicase DHR1

1

5

High-throughput

0.437

High

863882

RRP5
rRNA biogenesis protein RRP5

1

2

Small-scale

0.437

High

863883

RQC1
Ribosome quality control complex subunit 1

1

1

Small-scale

0.437

High

863884

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

1

High-throughput

0.437

High

863887

NVJ2
Nucleus-vacuole junction protein 2

1

1

High-throughput

0.437

High

863889

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

863894

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

863899

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

726161

2AAA
Protein phosphatase PP2A regulatory subunit A

1

0

High-throughput

0.426

High

804994

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.426

High

863892

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.426

High

561495

TBP
TATA-box-binding protein

1

1

High-throughput

0.407

High

584241

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

7

High-throughput

0.407

High

739888

RPD3
Histone deacetylase RPD3

1

5

High-throughput

0.407

High

757744

PIN4
RNA-binding protein PIN4

1

1

High-throughput

0.407

High

790509

CCL1
Cyclin CCL1

1

1

High-throughput

0.407

High

797936

YBP1
YAP1-binding protein 1

1

1

High-throughput

0.407

High

805487

TOM71
Protein TOM71

1

1

High-throughput

0.407

High

806473

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.407

High

823123

RFC2
Replication factor C subunit 2

1

1

High-throughput

0.407

High

863885

CFT1
Protein CFT1

1

1

High-throughput

0.407

High

863893

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.407

High

542975

CDC24
Cell division control protein 24

1

0

High-throughput

0.279

Low

740464

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.279

Low

826026

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.251

Low

364610

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.249

Low

417134

VDAC1
Non-selective voltage-gated ion channel 1

1

0

Small-scale

0.249

Low

554437

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

Small-scale

0.249

Low

734826

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.249

Low

746878

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

796975

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

863844

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

863854

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

863858

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

Small-scale

0.249

Low

863874

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

863877

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

863902

EFG1P
rRNA-processing protein EFG1

1

0

Small-scale

0.249

Low

863904

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

746042

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.232

Low

763459

MDJ1
DnaJ homolog 1, mitochondrial

1

0

High-throughput

0.232

Low

776375

YET1
Endoplasmic reticulum transmembrane protein 1

1

0

High-throughput

0.232

Low

795774

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

0

High-throughput

0.232

Low

798419

RGD1
RHO GTPase-activating protein RGD1

1

0

High-throughput

0.232

Low

812238

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

825587

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

863881

NTE1
Lysophospholipase NTE1

1

0

High-throughput

0.232

Low

863897

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025