HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: HXB5 (P09067)
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)
Gene: HOXB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 269
+	Hs
		433531 LYN_HUMAN (1-512): 0: 611: 100.00		HXC4_HUMAN (66-266): 1.77e-43: 150: 37.74
+	Hs
		447219 SRC_HUMAN (1-510): 0: 580: 51.97		HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00
+	Hs
		411952 FYN_HUMAN (1-510): 0: 576: 54.12		HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00
+	Hs
		433220 YES_HUMAN (1-510): 0: 572: 54.26		HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00
+	Hs
		522809 SRC_HUMAN (1-510): 0: 580: 51.97		HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30
+	Hs
		412230 FYN_HUMAN (1-510): 0: 576: 54.12		Q6FHY5_HUMAN (10-264): 3.75e-30: 116: 22.66
+	Hs
		412045 FYN_HUMAN (1-510): 0: 576: 54.12		HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30
+	Hs
		412088 FYN_HUMAN (1-510): 0: 576: 54.12		MEOX2_HUMAN (10-264): 7.22e-30: 115: 22.18
+	Hs
		412044 FYN_HUMAN (1-510): 0: 576: 54.12		HXA9_HUMAN (1-256): 8.04e-30: 114: 24.43
+	Hs
		337365 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30
+	Hs
		837944 BTK_HUMAN (2-505): 1.48e-156: 462: 33.86		MEOX2_HUMAN (10-264): 7.22e-30: 115: 22.18