HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: RADI (P35241)
Radixin
Gene: RDX

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23503679
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0030335 - positive regulation of cell migration GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 583
+	Hs
		433617 LYN_HUMAN (1-512): 0: 611: 100.00		MERL_HUMAN (2-583): 1.72e-151: 450: 45.30
+	Hs
		433240 YES_HUMAN (1-510): 0: 572: 54.26		EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28
+	Hs
		433541 LYN_HUMAN (1-512): 0: 611: 100.00		EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48
+	Hs
		434020 LYN_HUMAN (1-512): 0: 611: 100.00		E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55
+	Hs
		204599 LYN_HUMAN (1-512): 0: 611: 100.00		E41L2_HUMAN (2-543): 1.11e-118: 376: 19.46
+	Hs
		434004 LYN_HUMAN (1-512): 0: 611: 100.00		E41LB_HUMAN (4-540): 1.36e-118: 374: 18.26
+	Hs
		434008 LYN_HUMAN (1-512): 0: 611: 100.00		E41L1_HUMAN (3-495): 9.26e-119: 374: 21.94
+	Hs
		299230 LYN_HUMAN (1-512): 0: 611: 100.00		FARP2_HUMAN (2-582): 1.86e-110: 356: 18.76
+	Hs
		411867 LCK_HUMAN (1-512): 0: 582: 63.62		E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55
+	Hs
		434091 LYN_HUMAN (1-512): 0: 611: 100.00		E41L3_HUMAN (2-441): 2.82e-109: 353: 21.80
+	Hs
		411855 LCK_HUMAN (1-512): 0: 582: 63.62		E41L1_HUMAN (3-495): 9.26e-119: 374: 21.94
+	Hs
		412035 FYN_HUMAN (1-510): 0: 576: 54.12		PTN4_HUMAN (4-499): 2.34e-120: 379: 20.63
+	Hs
		411899 LCK_HUMAN (1-512): 0: 582: 63.62		E41L3_HUMAN (2-441): 2.82e-109: 353: 21.80
+	Hs
		523221 SRC_HUMAN (1-510): 0: 580: 51.97		E41L3_HUMAN (2-441): 2.82e-109: 353: 21.80
+	Hs
		412416 FYN_HUMAN (1-510): 0: 576: 54.12		E41L3_HUMAN (2-441): 2.82e-109: 353: 21.80
+	Hs
		523042 SRC_HUMAN (1-510): 0: 580: 51.97		FRMD5_HUMAN (1-350): 1.22e-108: 339: 24.65
+	Hs
		337358 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		PTN4_HUMAN (4-499): 2.34e-120: 379: 20.63
+	Hs
		337601 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		E41L3_HUMAN (2-441): 2.82e-109: 353: 21.80