HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: PK3CG (P48736)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)
Gene: PIK3CG

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 7721825, 10318860
Identification Methods affinity chromatography technology, pull down, affinity technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~SH2, PI3K_C2~SH2, PI3Ka~SH2
Common GO terms GO:0002250 - adaptive immune response
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 512
Hs

1 1102
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Last updated: 15 Jul 2024