Protein: TCPH
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta)

Gene: TCPH, CCT7
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: P42943

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005832 - chaperonin-containing T-complex
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

810831

TCPG
T-complex protein 1 subunit gamma

5

17

Small-scale

0.898

High

844426

2ABA
Protein phosphatase PP2A regulatory subunit B

3

20

High-throughput

0.852

High

844461

CMR1
DNA damage-binding protein CMR1

3

20

High-throughput

0.834

High

844424

ACT
Actin

3

20

Small-scale

0.805

High

810709

TCPB
T-complex protein 1 subunit beta

2

19

High-throughput

0.789

High

810966

TCPD
T-complex protein 1 subunit delta

2

16

High-throughput

0.789

High

811107

TCPZ
T-complex protein 1 subunit zeta

2

19

High-throughput

0.789

High

554011

TCPA
T-complex protein 1 subunit alpha

2

16

Small-scale

0.754

High

793940

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

2

20

High-throughput

0.714

High

386754

TBB
Tubulin beta chain

1

20

High-throughput

0.691

High

781882

CAF4
CCR4-associated factor 4

2

20

High-throughput

0.686

High

617404

GBB
Guanine nucleotide-binding protein subunit beta

1

20

High-throughput

0.646

High

637234

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.646

High

811595

PEX7
Peroxisomal targeting signal 2 receptor

1

20

High-throughput

0.646

High

684628

CDC20
APC/C activator protein CDC20

2

20

High-throughput

0.618

High

486223

TBA1
Tubulin alpha-1 chain

1

20

High-throughput

0.618

High

486479

TBA3
Tubulin alpha-3 chain

1

20

High-throughput

0.618

High

802069

ARP1
Centractin

1

20

High-throughput

0.618

High

823612

TCPE
T-complex protein 1 subunit epsilon

1

17

High-throughput

0.618

High

844407

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.618

High

844438

PLP1
Phosducin-like protein 1

1

16

High-throughput

0.618

High

633479

PP11
Serine/threonine-protein phosphatase PP1-1

2

20

High-throughput

0.611

High

820333

VID27
Vacuolar import and degradation protein 27

2

1

High-throughput

0.611

High

844453

PLP2
Phosducin-like protein 2

2

18

High-throughput

0.611

High

670845

SIS1
Protein SIS1

2

1

High-throughput

0.601

High

844420

CDH1
APC/C activator protein CDH1

2

20

Small-scale

0.594

High

844457

WTM1
Transcriptional modulator WTM1

2

1

High-throughput

0.594

High

364599

CDK1
Cyclin-dependent kinase 1

2

14

Small-scale

0.594

High

844408

HGH1
Protein HGH1

2

1

Small-scale

0.584

High

754296

DCA13
Protein SOF1

1

20

High-throughput

0.578

High

817584

UTP7
U3 small nucleolar RNA-associated protein 7

1

20

High-throughput

0.578

High

834761

LST8
Target of rapamycin complex subunit LST8

1

20

High-throughput

0.578

High

836044

COPB2
Coatomer subunit beta'

1

18

High-throughput

0.578

High

843168

PFS2
Polyadenylation factor subunit 2

1

20

High-throughput

0.578

High

844454

RAD28
Radiation-sensitive protein 28

1

20

High-throughput

0.578

High

844419

HOS2
Probable histone deacetylase HOS2

2

20

High-throughput

0.571

High

844406

MDV1
Mitochondrial division protein 1

1

20

High-throughput

0.553

High

844442

TAP42
Type 2A phosphatase-associated protein 42

2

9

High-throughput

0.537

High

844421

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

844429

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

5

High-throughput

0.536

High

844404

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

9

High-throughput

0.533

High

844446

UTP13
U3 small nucleolar RNA-associated protein 13

1

20

High-throughput

0.514

High

809080

DUN1
DNA damage response protein kinase DUN1

1

17

High-throughput

0.501

High

574695

KSS1
Mitogen-activated protein kinase KSS1

1

13

High-throughput

0.500

High

739886

RPD3
Histone deacetylase RPD3

1

20

Small-scale

0.500

High

744202

RAD24
Checkpoint protein RAD24

1

1

High-throughput

0.500

High

807235

SPT8
SAGA complex subunit SPT8

1

1

High-throughput

0.489

High

844415

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

6

High-throughput

0.489

High

656802

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.480

High

435168

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

436025

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

558771

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

579589

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.479

High

592326

VATB
V-type proton ATPase subunit B

1

10

High-throughput

0.479

High

603496

VATA
V-type proton ATPase catalytic subunit A

1

14

High-throughput

0.479

High

660800

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

20

High-throughput

0.479

High

674687

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

679805

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

709825

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

727116

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

737889

HOG1
Mitogen-activated protein kinase HOG1

1

14

High-throughput

0.479

High

747911

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

750704

PRS6A
26S proteasome regulatory subunit 6A

1

12

High-throughput

0.479

High

778386

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

794878

MAP2
Methionine aminopeptidase 2

1

4

High-throughput

0.479

High

802234

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

803590

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

844411

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

844412

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

844430

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

844431

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

2

High-throughput

0.479

High

844434

TOM1
E3 ubiquitin-protein ligase TOM1

1

12

High-throughput

0.479

High

844435

BUL2
Ubiquitin ligase-binding protein BUL2

1

2

Small-scale

0.479

High

844437

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.479

High

844440

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

844444

YMW4
Uncharacterized protein YMR074C

1

6

High-throughput

0.479

High

844451

SGO1
Shugoshin

1

1

High-throughput

0.479

High

844458

DBP10
ATP-dependent RNA helicase DBP10

1

6

High-throughput

0.479

High

844460

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.479

High

844436

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

844439

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

844455

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

795670

MOH1
Protein yippee-like MOH1

1

1

High-throughput

0.457

High

830128

NOP2
25S rRNA

1

1

High-throughput

0.457

High

368905

SYMC
Methionine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

394663

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

481659

HSP73
Heat shock protein SSA3

1

8

High-throughput

0.445

High

524289

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

526967

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

545273

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

557736

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.445

High

640560

UBC1
Ubiquitin-conjugating enzyme E2 1

1

1

High-throughput

0.445

High

647789

RFA1
Replication factor A protein 1

1

5

High-throughput

0.445

High

735893

MVD1
Diphosphomevalonate decarboxylase

1

1

High-throughput

0.445

High

795979

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

1

High-throughput

0.445

High

802873

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.445

High

816655

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.445

High

819044

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

844409

BUL1
Ubiquitin ligase-binding protein BUL1

1

2

High-throughput

0.445

High

844414

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

16

High-throughput

0.445

High

844428

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

19

High-throughput

0.445

High

383759

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

410194

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433702

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

441974

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

504272

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

512501

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

647145

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

660865

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

20

High-throughput

0.437

High

677454

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

707404

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

734131

EF2
Elongation factor 2

1

6

High-throughput

0.437

High

779265

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

796962

PHO88
SRP-independent targeting protein 3

1

1

High-throughput

0.437

High

805548

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

Small-scale

0.437

High

806746

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

812407

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

826586

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

844403

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

844422

SAM50
Sorting assembly machinery 50 kDa subunit

1

5

High-throughput

0.437

High

844427

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.437

High

844443

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

844448

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

844452

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

844463

ENV10
SRP-independent targeting protein 2

1

1

High-throughput

0.437

High

625965

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.426

High

738393

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.426

High

781094

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

High-throughput

0.426

High

836750

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

844405

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.426

High

844413

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.426

High

844416

ORC5
Origin recognition complex subunit 5

1

0

High-throughput

0.426

High

844418

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.426

High

844423

DAK1
Dihydroxyacetone kinase 1

1

0

High-throughput

0.426

High

844445

SWR1
Helicase SWR1

1

0

High-throughput

0.426

High

844450

NAT3
N-terminal acetyltransferase B complex catalytic subunit NAT3

1

0

High-throughput

0.426

High

844459

DPH6
Diphthine--ammonia ligase

1

0

High-throughput

0.426

High

419446

H2A1
Histone H2A.1

1

3

High-throughput

0.407

High

419776

H2A2
Histone H2A.2

1

3

High-throughput

0.407

High

676943

SRO9
RNA-binding protein SRO9

1

6

High-throughput

0.407

High

790508

CCL1
Cyclin CCL1

1

2

High-throughput

0.407

High

844410

HOSC
Homocitrate synthase, cytosolic isozyme

1

2

High-throughput

0.407

High

844417

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.407

High

844425

H3
Histone H3

1

5

High-throughput

0.407

High

844449

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

7

High-throughput

0.407

High

844462

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.407

High

808515

TEM1
Protein TEM1

1

0

High-throughput

0.261

Low

645256

GAS1
1,3-beta-glucanosyltransferase GAS1

1

0

High-throughput

0.249

Low

676647

SGF29
SAGA complex subunit SGF29

1

0

Small-scale

0.249

Low

747431

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

763923

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764101

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

844447

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

776479

MPE1
Protein MPE1

1

0

High-throughput

0.238

Low

381141

H2B1
Histone H2B.1

1

0

High-throughput

0.232

Low

586467

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.232

Low

736665

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

804114

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

High-throughput

0.232

Low

828486

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.232

Low

844432

SPP1
COMPASS component SPP1

1

0

High-throughput

0.232

Low

844433

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.232

Low

844441

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.232

Low

844456

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025