HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 196
+	Hs
		433685 LYN_HUMAN (1-512): 0: 611: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		433677 LYN_HUMAN (1-512): 0: 611: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		433556 LYN_HUMAN (1-512): 0: 611: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		433524 LYN_HUMAN (1-512): 0: 611: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		433671 LYN_HUMAN (1-512): 0: 611: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		433673 LYN_HUMAN (1-512): 0: 611: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		433565 LYN_HUMAN (1-512): 0: 611: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		522888 SRC_HUMAN (1-510): 0: 580: 51.97		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		120280 LYN_HUMAN (1-512): 0: 611: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		412123 FYN_HUMAN (1-510): 0: 576: 54.12		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		522885 SRC_HUMAN (1-510): 0: 580: 51.97		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		412115 FYN_HUMAN (1-510): 0: 576: 54.12		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		412120 FYN_HUMAN (1-510): 0: 576: 54.12		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		411980 FYN_HUMAN (1-510): 0: 576: 54.12		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		411948 FYN_HUMAN (1-510): 0: 576: 54.12		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		433239 YES_HUMAN (1-510): 0: 572: 54.26		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		412113 FYN_HUMAN (1-510): 0: 576: 54.12		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		433217 YES_HUMAN (1-510): 0: 572: 54.26		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		433244 YES_HUMAN (1-510): 0: 572: 54.26		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120279 YES_HUMAN (1-510): 0: 572: 54.26		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98