HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	22745667, 15190072, 9045636, 7516469
Identification Methods	unspecified method, fluorescent resonance energy transfer, affinity chromatography technology, enzymatic study, coimmunoprecipitation, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 443
+	Mm
		639447 LYN_MOUSE (1-512): 0: 612: 96.09		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		442815 HCK_HUMAN (1-512): 0: 595: 70.70		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		403437 SRC_MOUSE (1-510): 0: 577: 52.07		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Mm
		763394 FYN_MOUSE (1-510): 0: 576: 53.93		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		411689 LCK_HUMAN (1-512): 0: 582: 63.62		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		522933 SRC_HUMAN (1-510): 0: 580: 51.97		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		412149 FYN_HUMAN (1-510): 0: 576: 54.12		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		980964 YES_MOUSE (1-510): 0: 565: 54.28		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		433330 YES_HUMAN (1-510): 0: 572: 54.26		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		454827 FGR_HUMAN (1-510): 0: 562: 53.61		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		789110 FRK_HUMAN (32-506): 0: 528: 48.47		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		782780 CSK_HUMAN (64-503): 1.5e-171: 493: 38.41		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		433822 LYN_HUMAN (1-512): 0: 611: 100.00		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		991737 ITK_HUMAN (35-503): 3.09e-162: 475: 35.83		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991758 PTK6_HUMAN (58-506): 6.05e-162: 468: 38.55		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763412 FYN_MOUSE (1-510): 0: 576: 53.93		KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65
+	Hs
		1046410 PTK6_HUMAN (58-506): 6.05e-162: 468: 38.55		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Dm
		337713 SRC64_DROME (20-510): 3.4e-178: 513: 43.91		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		789069 ABL2_HUMAN (14-509): 1.38e-171: 517: 36.61		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		337484 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33