HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: PHC3 (Q8NDX5)
Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
Gene: PHC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SAM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 983
+	Hs
		433560 LYN_HUMAN (1-512): 0: 611: 100.00		MUC1_HUMAN (2-764): 1.79e-44: 177: 11.56
+	Hs
		411582 LCK_HUMAN (1-512): 0: 582: 63.62		MUC1_HUMAN (2-764): 1.79e-44: 177: 11.56
+	Hs
		522749 SRC_HUMAN (1-510): 0: 580: 51.97		MUC1_HUMAN (2-764): 1.79e-44: 177: 11.56
+	Hs
		523212 SRC_HUMAN (1-510): 0: 580: 51.97		SHAN2_HUMAN (2-980): 3.82e-32: 138: 10.61
+	Mm
		403435 SRC_MOUSE (1-510): 0: 577: 52.07		SHAN3_MOUSE (131-980): 1.72e-31: 135: 11.86
+	Hs
		523203 SRC_HUMAN (1-510): 0: 580: 51.97		SCML1_HUMAN (799-982): 6.24e-33: 132: 22.28
+	Hs
		523133 SRC_HUMAN (1-510): 0: 580: 51.97		SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53
+	Hs
		297808 LYN_HUMAN (1-512): 0: 611: 100.00		K0754_HUMAN (465-918): 1.77e-19: 97: 13.85
+	Hs
		412342 FYN_HUMAN (1-510): 0: 576: 54.12		SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53
+	Hs
		337335 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		MUC1_HUMAN (2-764): 1.79e-44: 177: 11.56
+	Hs
		64077 SRC_HUMAN (1-510): 0: 580: 51.97		L37A2_HUMAN (110-891): 4.67e-14: 79.3: 8.91
+	Hs
		433453 YES_HUMAN (1-510): 0: 572: 54.26		SAM11_HUMAN (915-979): 8.47e-15: 80.8: 49.23
+	Hs
		337552 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53