HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: UACA (Q9BZF9)
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene: UACA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1416
+	Hs
		434071 LYN_HUMAN (1-512): 0: 611: 100.00		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		433730 LYN_HUMAN (1-512): 0: 611: 100.00		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		411885 LCK_HUMAN (1-512): 0: 582: 63.62		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		411697 LCK_HUMAN (1-512): 0: 582: 63.62		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		434045 LYN_HUMAN (1-512): 0: 611: 100.00		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		523231 SRC_HUMAN (1-510): 0: 580: 51.97		MYH4_HUMAN (335-1286): 1.74e-33: 143: 12.12
+	Hs
		411877 LCK_HUMAN (1-512): 0: 582: 63.62		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		434072 LYN_HUMAN (1-512): 0: 611: 100.00		ANR50_HUMAN (180-367): 2.17e-10: 67.9: 15.07
+	Hs
		411590 LCK_HUMAN (1-512): 0: 582: 63.62		BCL3_HUMAN (95-260): 6.29e-10: 65.5: 29.14
+	Hs
		412002 FYN_HUMAN (1-510): 0: 576: 54.12		BCL3_HUMAN (95-260): 6.29e-10: 65.5: 29.14
+	Hs
		337406 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67