HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: ASNS (P08243)
Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase)
Gene: ASNS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 561
+	Hs
		337801 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		ASNS_HUMAN (1-561): 0: 712: 100.00
+	Hs
		384124 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		ASNS_HUMAN (1-561): 0: 712: 100.00
+	Hs
		438912 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		ASNS_HUMAN (1-561): 0: 712: 100.00
+	Hs
		438951 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		ASNS_HUMAN (1-561): 0: 712: 100.00
+	Hs
		438922 VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25		ASNS_HUMAN (1-561): 0: 712: 100.00
+	Hs
		384698 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		PUR1_HUMAN (2-283): 3.78e-62: 214: 15.81
+	Hs
		384699 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		GFPT1_HUMAN (1-223): 1.22e-46: 175: 12.80
+	Hs
		572625 VGFR1_HUMAN (716-1026): 5.28e-79: 285: 41.71		GFPT1_HUMAN (1-223): 1.22e-46: 175: 12.80