Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET
Interactor 2: PCDGH (Q9Y5G0)
Protocadherin gamma-B5 (PCDH-gamma-B5)
Gene: PCDHGB5
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32062451 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cadherin~Cadherin, Cadherin~Cadherin_2, Cadherin~RET_CLD1, Cadherin~RET_CLD3, Cadherin~RET_CLD4 |
| Common GO terms | GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
