HitPredict

Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 727
+	Hs
		451311 TPM1_HUMAN (1-284): 4.27e-46: 158: 85.56		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		419042 TPM3_HUMAN (1-284): 1.59e-44: 154: 86.27		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		297568 TPM3_HUMAN (1-284): 1.59e-44: 154: 86.27		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		932046 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		297602 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		451225 TPM1_HUMAN (1-284): 4.27e-46: 158: 85.56		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		434409 TPM2_HUMAN (1-284): 2.69e-41: 145: 100.00		ABTB2_HUMAN (231-647): 1.15e-77: 271: 17.08
+	Hs
		418937 TPM3_HUMAN (1-284): 1.59e-44: 154: 86.27		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		925177 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		931991 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19