Protein: RL21B
Large ribosomal subunit protein eL21B (60S ribosomal protein L21-B)

Gene: RL21B, RPL21B
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q12672

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol
GO:0022625 - cytosolic large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

684894

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.618

High

383212

RLA4
Large ribosomal subunit protein P2B

1

3

High-throughput

0.479

High

410414

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

415062

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

427495

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

427624

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.479

High

427767

RLA2
Large ribosomal subunit protein P2A

1

3

High-throughput

0.479

High

432747

RL7A
Large ribosomal subunit protein uL30A

1

3

High-throughput

0.479

High

432937

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

433321

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

434105

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

434468

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

434669

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

482108

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.479

High

503454

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

503868

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

509939

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

3

High-throughput

0.479

High

511323

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.479

High

511510

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

511608

RL44B
Large ribosomal subunit protein eL42B

1

1

High-throughput

0.479

High

513599

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

513801

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.479

High

514082

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

514388

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

515193

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

528885

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

531943

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

570197

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

663738

RL24B
Large ribosomal subunit protein eL24B

1

2

High-throughput

0.479

High

680196

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

689172

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.479

High

689300

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.479

High

712705

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.479

High

781285

RL14A
Large ribosomal subunit protein eL14A

1

3

High-throughput

0.479

High

792593

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

803449

RL14B
Large ribosomal subunit protein eL14B

1

3

High-throughput

0.479

High

806189

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

812799

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

813978

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

814065

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.479

High

825924

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

850286

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

863900

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

879861

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

879908

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

917712

LSG1
Large subunit GTPase 1

1

2

High-throughput

0.479

High

918353

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

1018169

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

1046335

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

1048432

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.479

High

1084081

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

511974

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

745926

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

865573

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.457

High

525676

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

528124

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

820222

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

1042415

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.445

High

567709

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

637309

PWP1
Periodic tryptophan protein 1

1

2

High-throughput

0.437

High

666573

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

677638

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

682437

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

708637

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

708810

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

735242

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

738948

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.437

High

790304

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

793551

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.437

High

798704

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

809447

STM1
Suppressor protein STM1

1

1

High-throughput

0.437

High

813729

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.437

High

815346

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

826967

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

844678

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

864204

ALB1
Ribosome biogenesis protein ALB1

1

1

High-throughput

0.437

High

865810

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

922699

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

1

Small-scale

0.437

High

924791

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.437

High

932264

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

1044244

ARX1
Probable metalloprotease ARX1

1

3

High-throughput

0.437

High

1046105

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.437

High

782505

RPF2
Ribosome biogenesis protein RPF2

1

1

High-throughput

0.407

High

1084248

NOP53
Ribosome biogenesis protein NOP53

1

1

Small-scale

0.407

High

364832

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.249

Low

808942

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

830224

NOP2
25S rRNA

1

0

Small-scale

0.249

Low

918741

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

1054884

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

1084430

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

863805

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025