Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: STE11 (P23561)
Serine/threonine-protein kinase STE11 (EC 2.7.11.25)
Gene: STE11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 12853477, 9180081, 15200959, 25689021, 22581371
Identification Methods affinity chromatography technology, pull down, enzymatic study, protein complementation assay, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0106310 - protein serine kinase activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 668
Sc

1 717
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp

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Last updated: 15 Jul 2024