Protein: RS3
Small ribosomal subunit protein uS3 (30S ribosomal protein S3)

Gene: RS3, rpsC
Organism: Escherichia coli K-12
Interactions: 224
UniProt ID: P0A7V3

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

493967

OBG
GTPase ObgE/CgtA

1

5

High-throughput

0.691

High

493876

CSPC
Cold shock-like protein CspC

3

8

High-throughput

0.657

High

493935

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

3

2

High-throughput

0.657

High

494009

DCYD
D-cysteine desulfhydrase

3

3

High-throughput

0.650

High

493914

NUSA
Transcription termination/antitermination protein NusA

3

0

High-throughput

0.629

High

490560

DER
GTPase Der

1

2

High-throughput

0.625

High

493840

RS5
Small ribosomal subunit protein uS5

1

3

High-throughput

0.625

High

493860

RPOB
DNA-directed RNA polymerase subunit beta

1

4

High-throughput

0.625

High

493875

CSPA
Cold shock protein CspA

2

8

High-throughput

0.612

High

421099

PNP
Polyribonucleotide nucleotidyltransferase

2

4

High-throughput

0.588

High

493871

LON
Lon protease

2

2

High-throughput

0.588

High

493923

SELB
Selenocysteine-specific elongation factor

2

4

High-throughput

0.588

High

493932

RNR
Ribonuclease R

2

2

High-throughput

0.588

High

493960

RLUB
Ribosomal large subunit pseudouridine synthase B

2

3

High-throughput

0.588

High

493976

RL4
Large ribosomal subunit protein uL4

2

2

High-throughput

0.588

High

493866

GLN1B
Glutamine synthetase

2

0

High-throughput

0.585

High

493847

TIG
Trigger factor

2

0

Small-scale

0.576

High

493904

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

493915

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.576

High

493839

RS4
Small ribosomal subunit protein uS4

1

1

High-throughput

0.575

High

395068

DNAA
Chromosomal replication initiator protein DnaA

2

0

High-throughput

0.563

High

490980

HSLO
33 kDa chaperonin

2

0

High-throughput

0.563

High

491922

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.563

High

492224

PYRH
Uridylate kinase

2

0

High-throughput

0.563

High

493842

RNH
Ribonuclease HI

2

0

High-throughput

0.563

High

493870

PHOL
PhoH-like protein

2

0

High-throughput

0.563

High

493879

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

493918

SPOT
Bifunctional

2

0

High-throughput

0.563

High

493938

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase PssA

2

0

High-throughput

0.563

High

493906

DCM
DNA-cytosine methyltransferase

2

2

High-throughput

0.549

High

491584

KPRS
Ribose-phosphate pyrophosphokinase

2

0

High-throughput

0.547

High

493924

TOP3
DNA topoisomerase 3

2

1

High-throughput

0.537

High

493968

HRPA
ATP-dependent RNA helicase HrpA

2

2

High-throughput

0.537

High

416314

SYE
Glutamate--tRNA ligase

1

1

High-throughput

0.536

High

491311

HSCA
Chaperone protein HscA

1

2

High-throughput

0.536

High

492859

RL27
Large ribosomal subunit protein bL27

1

1

High-throughput

0.536

High

493348

RS13
Small ribosomal subunit protein uS13

1

2

High-throughput

0.536

High

493841

RS9
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

493856

SYT
Threonine--tRNA ligase

1

3

High-throughput

0.536

High

493864

CSPG
Cold shock-like protein CspG

1

8

High-throughput

0.536

High

493869

RNG
Ribonuclease G

1

1

High-throughput

0.536

High

493873

GATD
Galactitol 1-phosphate 5-dehydrogenase

1

1

High-throughput

0.536

High

493877

RL13
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

493887

GLMU
Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase

1

2

High-throughput

0.536

High

493910

FLIA
RNA polymerase sigma factor FliA

1

1

High-throughput

0.536

High

493940

ACPS
Holo-[acyl-carrier-protein] synthase

1

1

High-throughput

0.536

High

493941

RECG
ATP-dependent DNA helicase RecG

1

3

High-throughput

0.536

High

493957

CSPB
Cold shock-like protein CspB

1

8

High-throughput

0.536

High

493974

RL2
Large ribosomal subunit protein uL2

1

1

High-throughput

0.536

High

493994

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

1

High-throughput

0.536

High

493999

YMFJ
Uncharacterized protein YmfJ

1

0

High-throughput

0.518

High

408520

3MG2
DNA-3-methyladenine glycosylase 2

1

0

High-throughput

0.513

High

490698

FIS
DNA-binding protein Fis

1

0

High-throughput

0.513

High

492418

RL11
Large ribosomal subunit protein uL11

1

0

High-throughput

0.513

High

493456

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.513

High

493848

TRPR
Trp operon repressor

1

0

High-throughput

0.513

High

493849

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

493853

YQGF
Putative pre-16S rRNA nuclease

1

0

High-throughput

0.513

High

493867

GLPX
Fructose-1,6-bisphosphatase 1 class 2

1

0

High-throughput

0.513

High

493868

MUG
G/U mismatch-specific DNA glycosylase

1

0

High-throughput

0.513

High

493880

YCED
Large ribosomal RNA subunit accumulation protein YceD

1

0

High-throughput

0.513

High

493883

BCCP
Biotin carboxyl carrier protein of acetyl-CoA carboxylase

1

0

High-throughput

0.513

High

493886

GLRX4
Glutaredoxin 4

1

0

High-throughput

0.513

High

493893

YMJA
Uncharacterized protein YmjA

1

0

High-throughput

0.513

High

493895

YFCZ
UPF0381 protein YfcZ

1

0

High-throughput

0.513

High

493900

RLMM
Ribosomal RNA large subunit methyltransferase M

1

0

High-throughput

0.513

High

493903

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

493905

RS15
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

493908

RIMO
Ribosomal protein uS12 methylthiotransferase RimO

1

0

High-throughput

0.513

High

493909

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

493912

TSAE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE

1

0

High-throughput

0.513

High

493917

SSPB
Stringent starvation protein B

1

0

High-throughput

0.513

High

493919

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

493920

SECB
Protein-export protein SecB

1

0

High-throughput

0.513

High

493928

MINC
Septum site-determining protein MinC

1

0

High-throughput

0.513

High

493959

WAAF
Lipopolysaccharide heptosyltransferase 2

1

0

High-throughput

0.513

High

493962

YGGL
Uncharacterized protein YggL

1

0

High-throughput

0.513

High

493964

RSMC
Ribosomal RNA small subunit methyltransferase C

1

0

High-throughput

0.513

High

493966

SPRT
Protein SprT

1

0

High-throughput

0.513

High

493984

RCNR
Transcriptional repressor RcnR

1

0

High-throughput

0.513

High

493990

CUTA
Divalent-cation tolerance protein CutA

1

0

High-throughput

0.513

High

494010

MTFA
Mlc titration factor A

1

0

High-throughput

0.513

High

493995

RLMI
Ribosomal RNA large subunit methyltransferase I

1

1

High-throughput

0.500

High

493925

ICLR
Transcriptional repressor IclR

1

0

High-throughput

0.493

High

367440

TRPE
Anthranilate synthase component 1

1

1

High-throughput

0.489

High

420163

ILVA
L-threonine dehydratase biosynthetic IlvA

1

3

High-throughput

0.489

High

469359

YCIH
Uncharacterized protein YciH

1

1

High-throughput

0.489

High

493889

MELR
Melibiose operon regulatory protein

1

2

High-throughput

0.489

High

493926

MUTY
Adenine DNA glycosylase

1

1

High-throughput

0.489

High

493927

PRIA
Replication restart protein PriA

1

8

High-throughput

0.489

High

493950

RLUF
Dual-specificity RNA pseudouridine synthase RluF

1

2

High-throughput

0.489

High

493978

GADW
HTH-type transcriptional regulator GadW

1

2

High-throughput

0.489

High

493997

RLUE
Ribosomal large subunit pseudouridine synthase E

1

2

High-throughput

0.489

High

494016

HSCC
Chaperone protein HscC

1

5

High-throughput

0.489

High

494017

WCAA
Putative colanic acid biosynthesis glycosyl transferase WcaA

1

1

High-throughput

0.489

High

365808

RPOD
RNA polymerase sigma factor RpoD

1

1

High-throughput

0.484

High

444275

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.484

High

469897

USG
USG-1 protein

1

1

High-throughput

0.484

High

492060

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.484

High

493844

RPOA
DNA-directed RNA polymerase subunit alpha

1

1

High-throughput

0.484

High

493855

RHLB
ATP-dependent RNA helicase RhlB

1

5

High-throughput

0.484

High

493858

SYK2
Lysine--tRNA ligase, heat inducible

1

3

High-throughput

0.484

High

493859

RPOC
DNA-directed RNA polymerase subunit beta'

1

3

High-throughput

0.484

High

493863

CSPD
Cold shock-like protein CspD

1

8

High-throughput

0.484

High

493872

DEAD
ATP-dependent RNA helicase DeaD

1

6

High-throughput

0.484

High

493878

RLUC
Ribosomal large subunit pseudouridine synthase C

1

3

High-throughput

0.484

High

493922

RCSB
Transcriptional regulatory protein RcsB

1

1

High-throughput

0.484

High

493933

SRMB
ATP-dependent RNA helicase SrmB

1

6

High-throughput

0.484

High

493934

RNE
Ribonuclease E

1

1

High-throughput

0.484

High

493936

MUKB
Chromosome partition protein MukB

1

2

High-throughput

0.484

High

493954

CBPA
Curved DNA-binding protein

1

1

High-throughput

0.484

High

493884

PCNB
Poly(A) polymerase I

1

0

High-throughput

0.479

High

493985

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.479

High

473253

DNAJ
Chaperone protein DnaJ

1

4

High-throughput

0.479

High

486843

GLTD
Glutamate synthase [NADPH] small chain

1

1

High-throughput

0.479

High

493930

PARE
DNA topoisomerase 4 subunit B

1

2

High-throughput

0.479

High

368949

SYGA
Glycine--tRNA ligase alpha subunit

1

0

High-throughput

0.464

High

445385

BIRA
Bifunctional ligase/repressor BirA

1

0

High-throughput

0.464

High

490663

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

490859

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

490953

IHFB
Integration host factor subunit beta

1

0

High-throughput

0.464

High

491479

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

0

High-throughput

0.464

High

491534

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

493846

SSRP
SsrA-binding protein

1

0

High-throughput

0.464

High

493852

UVRC
UvrABC system protein C

1

0

High-throughput

0.464

High

493874

ULAR
HTH-type transcriptional regulator UlaR

1

0

High-throughput

0.464

High

493888

HSLR
Heat shock protein 15

1

0

High-throughput

0.464

High

493921

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

493956

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

493963

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

1

0

High-throughput

0.464

High

493996

NPD
NAD-dependent protein deacylase

1

0

High-throughput

0.464

High

490630

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.458

High

493850

RIMP
Ribosome maturation factor RimP

1

0

High-throughput

0.458

High

493857

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

493861

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

493898

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.458

High

493937

ISPA
Farnesyl diphosphate synthase

1

0

High-throughput

0.458

High

493939

PHOP
Transcriptional regulatory protein PhoP

1

0

High-throughput

0.458

High

493979

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.458

High

493980

YDCY
Uncharacterized protein YdcY

1

0

High-throughput

0.458

High

493991

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

494013

YFFS
Uncharacterized protein YffS

1

0

High-throughput

0.458

High

494020

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.458

High

493890

CRA
Catabolite repressor/activator

1

1

High-throughput

0.442

High

493882

ATPG
ATP synthase gamma chain

1

1

High-throughput

0.437

High

493955

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

1

High-throughput

0.437

High

494015

GTRB
Prophage bactoprenol glucosyl transferase homolog

1

1

High-throughput

0.437

High

493896

FIMB
Type 1 fimbriae regulatory protein FimB

3

0

High-throughput

0.342

High

493851

YACL
UPF0231 protein YacL

2

0

High-throughput

0.307

High

493993

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

493899

LPTM
LPS-assembly lipoprotein LptM

1

0

High-throughput

0.282

High

493987

YGDI
Uncharacterized lipoprotein YgdI

1

0

High-throughput

0.282

High

360231

NDH
Type II NADH:quinone oxidoreductase

1

0

High-throughput

0.279

Low

438974

ADA
Bifunctional transcriptional activator/DNA repair enzyme Ada

1

0

High-throughput

0.279

Low

444243

BTUE
Thioredoxin/glutathione peroxidase BtuE

1

0

High-throughput

0.279

Low

450107

PRIB
Replication restart protein PriB

1

0

High-throughput

0.279

Low

479584

YJAA
Uncharacterized protein YjaA

1

0

High-throughput

0.279

Low

492320

RECO
DNA repair protein RecO

1

0

High-throughput

0.279

Low

493845

SMG
Protein Smg

1

0

High-throughput

0.279

Low

493881

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

493885

FLAW
Flavodoxin 2

1

0

High-throughput

0.279

Low

493891

LPXL
Lipid A biosynthesis lauroyltransferase

1

0

High-throughput

0.279

Low

493894

YDIE
Uncharacterized protein YdiE

1

0

High-throughput

0.279

Low

493897

PINR
Serine recombinase PinR

1

0

High-throughput

0.279

Low

493902

YGIC
Putative acid--amine ligase YgiC

1

0

High-throughput

0.279

Low

493907

DMA
DNA adenine methylase

1

0

High-throughput

0.279

Low

493911

HYCI
Hydrogenase 3 maturation protease

1

0

High-throughput

0.279

Low

493913

YJFI
Uncharacterized protein YjfI

1

0

High-throughput

0.279

Low

493916

MEPS
Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase

1

0

High-throughput

0.279

Low

493929

HYAF
Hydrogenase-1 operon protein HyaF

1

0

High-throughput

0.279

Low

493931

SPEA
Biosynthetic arginine decarboxylase

1

0

High-throughput

0.279

Low

493942

RP54
RNA polymerase sigma-54 factor

1

0

High-throughput

0.279

Low

493944

WAAG
Lipopolysaccharide glucosyltransferase WaaG

1

0

High-throughput

0.279

Low

493945

WAAY
Lipopolysaccharide core heptose(II) kinase WaaY

1

0

High-throughput

0.279

Low

493946

ROXA
Ribosomal protein uL16 3-hydroxylase

1

0

High-throughput

0.279

Low

493949

CBRC
UPF0167 protein CbrC

1

0

High-throughput

0.279

Low

493951

MDTN
Multidrug resistance protein MdtN

1

0

High-throughput

0.279

Low

493952

OPGG
Glucans biosynthesis protein G

1

0

High-throughput

0.279

Low

493958

YCHJ
UPF0225 protein YchJ

1

0

High-throughput

0.279

Low

493969

YHBQ
UPF0213 protein YhbQ

1

0

High-throughput

0.279

Low

493971

YGFF
Uncharacterized oxidoreductase YgfF

1

0

High-throughput

0.279

Low

493972

RATB
UPF0125 protein RatB

1

0

High-throughput

0.279

Low

493975

FIXA
Protein FixA

1

0

High-throughput

0.279

Low

493982

YDIZ
Uncharacterized protein YdiZ

1

0

High-throughput

0.279

Low

493986

YHCO
Uncharacterized protein YhcO

1

0

High-throughput

0.279

Low

493988

DIAA
DnaA initiator-associating protein DiaA

1

0

High-throughput

0.279

Low

493989

HIGA
Antitoxin HigA

1

0

High-throughput

0.279

Low

493992

WCAK
Colanic acid biosynthesis protein WcaK

1

0

High-throughput

0.279

Low

493998

YMFD
Uncharacterized protein YmfD

1

0

High-throughput

0.279

Low

494000

YMGA
Probable two-component-system connector protein YmgA

1

0

High-throughput

0.279

Low

494001

YCGY
Uncharacterized protein YcgY

1

0

High-throughput

0.279

Low

494002

YNAE
Uncharacterized protein YnaE

1

0

High-throughput

0.279

Low

494006

YNEG
Uncharacterized protein YneG

1

0

High-throughput

0.279

Low

494007

YNJA
Uncharacterized protein YnjA

1

0

High-throughput

0.279

Low

494011

YFDS
Uncharacterized protein YfdS

1

0

High-throughput

0.279

Low

494012

YPEA
Acetyltransferase YpeA

1

0

High-throughput

0.279

Low

494014

YPJB
Protein YpjB

1

0

High-throughput

0.279

Low

494018

FLXA
Protein FlxA

1

0

High-throughput

0.279

Low

494021

MQSR
mRNA interferase toxin MqsR

1

0

High-throughput

0.279

Low

494022

CSE1
CRISPR system Cascade subunit CasA

1

0

High-throughput

0.279

Low

494023

YAFP
Uncharacterized N-acetyltransferase YafP

1

0

High-throughput

0.279

Low

493901

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

493983

YODC
Uncharacterized protein YodC

1

0

High-throughput

0.261

Low

492026

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

493843

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

493854

TRMB
tRNA

1

0

High-throughput

0.253

Low

493947

HOLA
DNA polymerase III subunit delta

1

0

High-throughput

0.253

Low

493953

NIKE
Nickel import ATP-binding protein NikE

1

0

High-throughput

0.253

Low

493981

YDIH
Uncharacterized protein YdiH

1

0

High-throughput

0.253

Low

494004

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

0

High-throughput

0.253

Low

493862

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

493865

GLPC
Anaerobic glycerol-3-phosphate dehydrogenase subunit C

1

0

High-throughput

0.249

Low

493892

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.249

Low

493943

YIDC
Membrane protein insertase YidC

1

0

Small-scale

0.249

Low

493948

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.249

Low

493961

USPF
Universal stress protein F

1

0

High-throughput

0.249

Low

493965

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low

493970

YHDP
Intermembrane phospholipid transporter YhdP

1

0

High-throughput

0.249

Low

493973

CSIE
Stationary phase-inducible protein CsiE

1

0

High-throughput

0.249

Low

493977

LOLB
Outer-membrane lipoprotein LolB

1

0

High-throughput

0.249

Low

494003

INSQ
Putative RNA-guided DNA endonuclease InsQ

1

0

High-throughput

0.249

Low

494005

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

494008

YEAO
Uncharacterized protein YeaO

1

0

High-throughput

0.249

Low

494019

YBAY
Uncharacterized lipoprotein YbaY

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025