HitPredict

Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15849318
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0017053 - transcription repressor complex GO:0042826 - histone deacetylase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 785 Hs			1 191
+	Hs
		728565 ZNF93_HUMAN (207-784): 8.84e-171: 507: 13.51		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		1027123 ZN283_HUMAN (306-784): 2.48e-142: 436: 15.21		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		316017 ZNF92_HUMAN (207-731): 2.21e-128: 397: 10.45		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18
+	Hs
		1027201 ZN570_HUMAN (465-778): 4.21e-91: 298: 16.72		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		800409 ZN569_HUMAN (331-628): 1.5e-81: 276: 7.79		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		1027143 ZN420_HUMAN (319-642): 2.08e-82: 279: 9.76		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		1027217 ZN184_HUMAN (601-785): 1.12e-77: 267: 21.16		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		599068 ZNF10_HUMAN (566-784): 2.17e-78: 265: 20.17		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		800424 ZFP1_HUMAN (546-783): 2.14e-63: 219: 19.01		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		1027061 ZFP1_HUMAN (546-783): 2.14e-63: 219: 19.01		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		800406 Z585B_HUMAN (331-598): 3.59e-51: 193: 6.23		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		800425 Z585A_HUMAN (331-598): 4.46e-51: 193: 6.23		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		949817 ZFP1_HUMAN (546-783): 2.14e-63: 219: 19.01		CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65
+	Hs
		316021 ZN33B_HUMAN (459-784): 1.08e-80: 276: 15.24		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18
+	Hs
		123331 ZKSC7_HUMAN (36-684): 2.93e-76: 264: 11.63		CBX4_HUMAN (11-125): 7.54e-26: 105: 25.22
+	Hs
		316135 ZN184_HUMAN (601-785): 1.12e-77: 267: 21.16		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18
+	Hs
		316188 ZKSC7_HUMAN (36-684): 2.93e-76: 264: 11.63		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18
+	Hs
		1059199 ZKSC7_HUMAN (36-684): 2.93e-76: 264: 11.63		CBX2_HUMAN (10-111): 5.1e-24: 99.9: 31.37
+	Hs
		203785 ZN436_HUMAN (572-709): 8.69e-57: 203: 33.80		SUV91_HUMAN (4-135): 2.04e-36: 132: 19.70
+	Hs
		315990 ZN121_HUMAN (538-723): 1.06e-55: 198: 25.24		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18