Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 11448933, 21645859, 17586502
Identification Methods anti tag coimmunoprecipitation, molecular sieving, static light scattering, comigration in sds page, protein kinase assay
Interaction Type physical association, direct interaction, covalent binding, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3, Furin-like~Furin-like, Furin-like~Recep_L_domain, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, Recep_L_domain~Recep_L_domain
Common GO terms GO:0001965 - G-protein alpha-subunit binding
GO:0003230 - cardiac atrium development
GO:0004713 - protein tyrosine kinase activity
GO:0005009 - insulin receptor activity
GO:0005010 - insulin-like growth factor receptor activity
and 71 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1367
Hs

1 1367
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Last updated: 15 Jul 2024