Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R
Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.76 | 1.00 | 0.873 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11448933, 21645859, 17586502 |
Identification Methods | anti tag coimmunoprecipitation, molecular sieving, static light scattering, comigration in sds page, protein kinase assay |
Interaction Type | physical association, direct interaction, covalent binding, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | fn3~fn3, Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3, Furin-like~Furin-like, Furin-like~Recep_L_domain, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, Recep_L_domain~Recep_L_domain |
Common GO terms | GO:0001965 - G-protein alpha-subunit binding GO:0003230 - cardiac atrium development GO:0004713 - protein tyrosine kinase activity GO:0005009 - insulin receptor activity GO:0005010 - insulin-like growth factor receptor activity and 71 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024