HitPredict

Interactor 1: CUL3 (P53202)
Cullin-3 (Cullin-B)
Gene: CUL3

Interactor 2: RBX1 (Q08273)
RING-box protein HRT1 (RING-box protein 1) (E3 ubiquitin-protein ligase complex SCF subunit HRT1) (High level expression reduces Ty3 transposition protein 1) (Regulator of cullins protein 1)
Gene: HRT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.883

The method score is based on:

Property Details
Experiments 12676951, 18719252, 37968396, 19882662
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006289 - nucleotide-excision repair
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 744
Sc

1 121
+ At
+ Mm
+ Hs
+ At
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Mm
+ At
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024