HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: RHG01 (Q07960)
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)
Gene: ARHGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 439
+	Hs
		411366 INSR_HUMAN (32-1365): 0: 1219: 56.54		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Rn
		88969 INSR_RAT (20-1365): 0: 1210: 55.45		D4A9G6_RAT (205-438): 5.91e-65: 227: 24.90
+	Rn
		88844 D3ZZK3_RAT (655-1341): 0: 564: 23.43		CHIN_RAT (187-431): 2.29e-68: 222: 21.12
+	Mm
		975149 EPHA4_MOUSE (655-1342): 0: 565: 23.54		CHIN_MOUSE (187-431): 2.63e-66: 220: 21.12
+	Hs
		64749 EPHA6_HUMAN (653-1297): 7.23e-167: 528: 23.27		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		64659 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		507962 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Hs
		993022 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Hs
		64712 NTRK2_HUMAN (977-1256): 2.65e-70: 255: 43.95		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		64640 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		64625 MUSK_HUMAN (993-1262): 8.25e-69: 251: 42.96		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Mm
		546314 NTRK2_MOUSE (977-1262): 3.02e-69: 252: 43.05		RHG32_MOUSE (180-435): 3.64e-63: 222: 21.40
+	Hs
		507973 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		BNIP2_HUMAN (4-228): 1.04e-71: 230: 29.46
+	Hs
		64711 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		384998 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		RHG17_HUMAN (242-405): 2.45e-19: 92.8: 32.73
+	Hs
		384788 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		MYO9B_HUMAN (235-427): 3.06e-18: 89.7: 30.96
+	Hs
		601861 ERBB3_HUMAN (15-362): 5.41e-25: 115: 18.88		CHIO_HUMAN (187-431): 1.49e-64: 216: 21.91
+	Hs
		64660 EPHB2_HUMAN (496-674): 6.85e-19: 95.5: 17.88		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56