Protein: NU100
Nucleoporin NUP100/NSP100 (Nuclear pore protein NUP100/NSP100)

Gene: NU100, NUP100
Organism: Saccharomyces cerevisiae S288C
Interactions: 92
UniProt ID: Q02629

Gene Ontology (top 5):
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003723 - RNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006405 - RNA export from nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1037950

NU116
Nucleoporin NUP116/NSP116

7

20

Small-scale

0.965

High

886200

NU145
Nucleoporin NUP145

5

19

Small-scale

0.922

High

1037949

NU100
Nucleoporin NUP100/NSP100

3

19

Small-scale

0.840

High

1037961

IMB1
Importin subunit beta-1

13

20

Small-scale

0.760

High

914990

NUP84
Nucleoporin NUP84

8

16

Small-scale

0.746

High

858318

NUP85
Nucleoporin NUP85

6

9

Small-scale

0.729

High

823496

NUP82
Nucleoporin NUP82

6

8

Small-scale

0.727

High

1037969

MEX67
mRNA export factor MEX67

6

19

Small-scale

0.725

High

912746

NU188
Nucleoporin NUP188

6

8

Small-scale

0.720

High

776539

NU120
Nucleoporin NUP120

5

8

Small-scale

0.714

High

795162

NU170
Nucleoporin NUP170

5

20

Small-scale

0.714

High

782548

NU133
Nucleoporin NUP133

5

13

Small-scale

0.713

High

734716

IMB3
Importin subunit beta-3

5

20

Small-scale

0.704

High

722187

XPO1
Exportin-1

4

20

Small-scale

0.674

High

915393

MSN5
Protein MSN5

4

20

Small-scale

0.674

High

756654

NIC96
Nucleoporin NIC96

3

17

Small-scale

0.667

High

1037956

ARX1
Probable metalloprotease ARX1

5

7

Small-scale

0.648

High

817933

IMB4
Importin subunit beta-4

3

20

Small-scale

0.646

High

577334

NSP1
Nucleoporin NSP1

3

19

Small-scale

0.640

High

738500

NUP2
Nucleoporin NUP2

3

20

Small-scale

0.640

High

796113

IMB2
Importin subunit beta-2

3

20

Small-scale

0.640

High

825170

NU159
Nucleoporin NUP159

3

19

Small-scale

0.640

High

1036908

MLP1
Protein MLP1

3

20

High-throughput

0.640

High

1037951

IMA1
Importin subunit alpha

3

20

Small-scale

0.640

High

1037957

SXM1
Importin beta SMX1

3

20

Small-scale

0.640

High

817815

NU157
Nucleoporin NUP157

2

20

Small-scale

0.640

High

864643

NU192
Nucleoporin NUP192

2

17

Small-scale

0.624

High

877971

NUP57
Nucleoporin NUP57

2

19

Small-scale

0.620

High

1037965

GLE1
mRNA export factor GLE1

2

13

Small-scale

0.600

High

886172

NUP42
Nucleoporin NUP42

2

19

Small-scale

0.595

High

1035262

NUP49
Nucleoporin NUP49/NSP49

2

19

Small-scale

0.595

High

1037960

NUP59
Nucleoporin ASM4

2

14

Small-scale

0.595

High

527476

HSP72
Heat shock protein SSA2

3

18

Small-scale

0.585

High

403629

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

6

Small-scale

0.584

High

634269

NUP1
Nucleoporin NUP1

2

19

Small-scale

0.584

High

1037953

KA120
Importin beta-like protein KAP120

2

20

Small-scale

0.584

High

1037970

HRP1
Nuclear polyadenylated RNA-binding protein 4

2

8

Small-scale

0.584

High

916420

SEH1
Nucleoporin SEH1

1

20

Small-scale

0.561

High

1037958

SEC13
Protein transport protein SEC13

1

20

Small-scale

0.561

High

721656

RENT1
ATP-dependent helicase NAM7

1

3

Small-scale

0.552

High

808601

SMC2
Structural maintenance of chromosomes protein 2

2

2

Small-scale

0.533

High

1037966

RTP1
RNA polymerase II assembly factor RTP1

1

1

Small-scale

0.527

High

819566

SSB2
Ribosome-associated molecular chaperone SSB2

2

16

High-throughput

0.504

High

758046

MTR2
mRNA transport regulator MTR2

1

6

Small-scale

0.501

High

1037967

RRP12
Ribosomal RNA-processing protein 12

1

2

Small-scale

0.501

High

667112

CG22
G2/mitotic-specific cyclin-2

1

6

High-throughput

0.489

High

667149

CG23
G2/mitotic-specific cyclin-3

1

6

High-throughput

0.489

High

513751

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

524898

HSP71
Heat shock protein SSA1

1

18

Small-scale

0.479

High

792915

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

803810

BRL1
Nucleus export protein BRL1

1

5

Small-scale

0.479

High

813427

PO152
Nucleoporin POM152

1

8

High-throughput

0.479

High

813648

NUP60
Nucleoporin NUP60

1

5

Small-scale

0.479

High

817847

GLE2
mRNA export factor GLE2

1

20

Small-scale

0.479

High

858350

SAC3
Nuclear mRNA export protein SAC3

1

6

High-throughput

0.479

High

1037952

NOG1
Nucleolar GTP-binding protein 1

1

5

High-throughput

0.479

High

1037954

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

1037964

YRA1
RNA annealing protein YRA1

1

8

Small-scale

0.479

High

825240

SEC24
Protein transport protein SEC24

1

6

High-throughput

0.464

High

850466

LSB3
LAS seventeen-binding protein 3

1

1

High-throughput

0.464

High

916549

TEL2
Telomere length regulation protein TEL2

1

1

High-throughput

0.464

High

1037962

BUD20
Bud site selection protein 20

1

3

Small-scale

0.457

High

745102

AFG2
ATPase family gene 2 protein

1

7

Small-scale

0.439

High

865479

BFA1
Mitotic check point protein BFA1

1

1

Small-scale

0.439

High

149912

RS9A
Small ribosomal subunit protein uS4A

1

1

Small-scale

0.437

High

435622

RS9B
Small ribosomal subunit protein uS4B

1

1

Small-scale

0.437

High

503197

RS22A
Small ribosomal subunit protein uS8A

1

2

Small-scale

0.437

High

510747

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.437

High

671038

SIS1
Protein SIS1

1

3

High-throughput

0.437

High

738907

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

8

High-throughput

0.437

High

795502

ATG8
Autophagy-related protein 8

1

14

Small-scale

0.437

High

864232

MDV1
Mitochondrial division protein 1

1

11

Small-scale

0.437

High

893286

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

13

High-throughput

0.437

High

925373

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

1037955

RMT2
Protein arginine N-methyltransferase 2

1

3

Small-scale

0.437

High

1037959

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.437

High

1037963

AP3D
AP-3 complex subunit delta

1

8

High-throughput

0.437

High

1037968

RS22B
Small ribosomal subunit protein uS8B

1

2

Small-scale

0.437

High

874258

CLA4
Serine/threonine-protein kinase CLA4

1

1

High-throughput

0.417

High

916517

MIG2
Regulatory protein MIG2

1

4

High-throughput

0.417

High

1035039

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.417

High

545967

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.407

High

651980

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

6

High-throughput

0.407

High

735794

TFC1
Transcription factor tau 95 kDa subunit

2

0

Small-scale

0.305

High

923793

TOF1
Topoisomerase 1-associated factor 1

2

0

Small-scale

0.305

High

674427

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.249

Low

678997

NOT1
General negative regulator of transcription subunit 1

1

0

Small-scale

0.249

Low

692523

GYS2
Glycogen [starch] synthase isoform 2

1

0

Small-scale

0.249

Low

923740

CAF40
Protein CAF40

1

0

Small-scale

0.249

Low

797939

YBP1
YAP1-binding protein 1

1

0

High-throughput

0.238

Low

830018

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025