HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: SLAF1 (Q13291)
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)
Gene: SLAMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1367 Hs			1 335
+	Hs
		435514 IGF1R_HUMAN (1-1367): 0: 1387: 100.00		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		435501 IGF1R_HUMAN (1-1367): 0: 1387: 100.00		CD48_HUMAN (35-256): 1.1e-43: 152: 23.66
+	Hs
		665394 EPHA3_HUMAN (666-1311): 0: 564: 24.96		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Hs
		665402 EPHA3_HUMAN (666-1311): 0: 564: 24.96		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		507926 EPHA4_HUMAN (655-1342): 8.85e-179: 558: 23.12		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		872657 EPHA4_HUMAN (655-1342): 8.85e-179: 558: 23.12		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		665204 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		CXAR_HUMAN (10-334): 1.04e-51: 176: 13.68
+	Hs
		507871 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		601484 EPHA4_HUMAN (655-1342): 8.85e-179: 558: 23.12		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		601465 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		665239 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		OPCM_HUMAN (19-258): 6.48e-24: 102: 10.08
+	Hs
		685227 EPHB4_HUMAN (648-1305): 5.48e-162: 514: 23.20		CEAM8_HUMAN (45-251): 6.59e-22: 96.5: 16.51
+	Mm
		546293 NTRK2_MOUSE (977-1262): 3.02e-69: 252: 43.05		CXAR_MOUSE (10-334): 3.08e-54: 183: 14.12
+	Hs
		507812 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		508034 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		507857 FGFR3_HUMAN (972-1266): 2.05e-63: 234: 38.44		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		68223 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		HECA2_HUMAN (1-329): 2.97e-24: 104: 17.39
+	Hs
		507854 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		508005 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		OPCM_HUMAN (19-258): 6.48e-24: 102: 10.08
+	Hs
		601456 FGFR3_HUMAN (972-1266): 2.05e-63: 234: 38.44		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29