HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: CLCC1 (Q96S66)
Chloride channel CLIC-like protein 1 (Mid-1-related chloride channel protein 1)
Gene: CLCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 551
+	Hs
		411478 INSR_HUMAN (32-1365): 0: 1219: 56.54		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		537766 INSRR_HUMAN (14-1310): 0: 1170: 55.26		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		872474 EPHA5_HUMAN (666-1275): 2.52e-173: 545: 24.01		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		665517 EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		1301880 ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		385383 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		169197 MUSK_HUMAN (993-1262): 8.25e-69: 251: 42.96		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		508157 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		1081573 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		CLCC1_HUMAN (1-551): 0: 1108: 100.00
+	Hs
		445872 ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47		CLCC1_HUMAN (1-551): 0: 1108: 100.00