Protein: EI2BD
Translation initiation factor eIF2B subunit delta (GCD complex subunit GCD2) (Guanine nucleotide exchange factor subunit GCD2) (eIF2B GDP-GTP exchange factor subunit delta)

Gene: EI2BD, GCD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P12754

Gene Ontology (top 5):
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
GO:0006446 - regulation of translational initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

555297

EI2BE
Translation initiation factor eIF2B subunit epsilon

12

15

Small-scale

0.981

High

555298

EI2BB
Translation initiation factor eIF2B subunit beta

11

15

Small-scale

0.979

High

555284

EI2BA
Translation initiation factor eIF2B subunit alpha

8

14

Small-scale

0.971

High

555288

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

6

4

Small-scale

0.944

High

478386

EI2BG
Translation initiation factor eIF2B subunit gamma

14

15

Small-scale

0.763

High

555296

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

6

7

Small-scale

0.732

High

478577

IF2B
Eukaryotic translation initiation factor 2 subunit beta

3

7

Small-scale

0.646

High

555294

BMH1
Protein BMH1

2

4

High-throughput

0.543

High

555319

IST1
Vacuolar protein sorting-associated protein IST1

2

2

High-throughput

0.537

High

555316

FKH1
Fork head protein homolog 1

1

3

High-throughput

0.536

High

555286

VATB
V-type proton ATPase subunit B

2

2

High-throughput

0.533

High

555308

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

2

2

Small-scale

0.521

High

555310

KOG1
Target of rapamycin complex 1 subunit KOG1

1

6

High-throughput

0.504

High

358949

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

4

High-throughput

0.500

High

359417

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

4

High-throughput

0.500

High

367668

ENO1
Enolase 1

1

2

High-throughput

0.500

High

405006

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.500

High

408545

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

2

High-throughput

0.500

High

439215

PDC1
Pyruvate decarboxylase isozyme 1

1

3

High-throughput

0.500

High

555314

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.500

High

555287

TUP1
General transcriptional corepressor TUP1

1

3

High-throughput

0.489

High

555295

XPO1
Exportin-1

1

10

High-throughput

0.489

High

409895

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

434764

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

435727

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

436300

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

6

High-throughput

0.479

High

441660

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

454826

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

514410

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

555289

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

555291

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

555300

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

555302

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

555304

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

555309

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

555313

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

555318

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

555321

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

555323

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

555325

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

433403

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

512215

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

512774

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

555292

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

555301

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

555324

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

456319

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

3

High-throughput

0.457

High

555285

HSP26
Heat shock protein 26

1

5

High-throughput

0.457

High

555320

ACT
Actin

1

2

High-throughput

0.457

High

453387

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

522883

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

525772

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

543629

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

555290

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

555299

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

555303

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.445

High

555315

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

555293

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

555306

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.437

High

555307

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

555312

XDJ1
DnaJ protein homolog XDJ1

1

3

High-throughput

0.437

High

555322

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

386541

TBB
Tubulin beta chain

1

2

High-throughput

0.407

High

555326

HSP42
Heat shock protein 42

1

5

High-throughput

0.407

High

439073

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

555305

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.261

Low

555317

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.261

Low

555311

STM1
Suppressor protein STM1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025