HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030335 - positive regulation of cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1130
+	Hs
		613234 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613239 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613241 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		639881 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		419186 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419189 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419135 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		419191 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		530601 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		443063 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443068 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		436126 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443071 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		880209 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		880211 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		436228 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		566867 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566873 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566875 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Rn
		901292 RHOA_RAT (1-193): 7.11e-82: 242: 92.23		Q9WUP8_RAT (943-1088): 3.85e-28: 113: 30.87