Interactor 1: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2

Interactor 2: YLAT2 (Q92536)
Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)
Gene: SLC7A6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 35271311, 11507094
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease_2~Alpha-amylase, AA_permease_2~SLC3A2_N
Common GO terms GO:0005886 - plasma membrane
GO:0015820 - L-leucine transport
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 630
Hs

1 515
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Mm
+ Dm

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Last updated: 15 Jul 2024