HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: FER (P16591)
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)
Gene: FER

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32707033, 22939624
Identification Methods	affinity chromatography technology, pull down, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 822
+	Hs
		426937 HS90B_HUMAN (1-724): 0: 1086: 100.00		FES_HUMAN (1-820): 0: 786: 49.94
+	Hs
		69196 HS90B_HUMAN (1-724): 0: 1086: 100.00		A9UEZ6_HUMAN (306-822): 8.13e-157: 499: 32.22
+	Hs
		337314 HS90B_HUMAN (1-724): 0: 1086: 100.00		ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75
+	Hs
		337312 HS90A_HUMAN (1-724): 0: 1072: 85.25		ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75
+	Hs
		433218 HS90B_HUMAN (1-724): 0: 1086: 100.00		YES_HUMAN (319-816): 7.62e-160: 477: 31.45
+	Hs
		437966 HS90B_HUMAN (1-724): 0: 1086: 100.00		ABL2_HUMAN (291-822): 9.93e-152: 476: 30.90
+	Hs
		433526 HS90B_HUMAN (1-724): 0: 1086: 100.00		LYN_HUMAN (372-817): 5.02e-159: 474: 32.26
+	Hs
		437847 HS90B_HUMAN (1-724): 0: 1086: 100.00		SRC_HUMAN (329-816): 4.13e-158: 473: 31.95
+	Hs
		437967 HS90B_HUMAN (1-724): 0: 1086: 100.00		FRK_HUMAN (398-815): 1.29e-158: 473: 33.41
+	Hs
		438007 HS90B_HUMAN (1-724): 0: 1086: 100.00		BLK_HUMAN (358-817): 1.59e-156: 467: 29.77
+	Hs
		411949 HS90B_HUMAN (1-724): 0: 1086: 100.00		FYN_HUMAN (335-816): 7.37e-155: 464: 30.60
+	Hs
		437817 HS90B_HUMAN (1-724): 0: 1086: 100.00		HCK_HUMAN (333-817): 2.45e-154: 463: 30.26
+	Hs
		438525 HS90B_HUMAN (1-724): 0: 1086: 100.00		SRMS_HUMAN (399-819): 3.7e-154: 461: 34.57
+	Hs
		438107 HS90B_HUMAN (1-724): 0: 1086: 100.00		ITK_HUMAN (370-820): 4.11e-151: 458: 29.90
+	Hs
		437823 HS90B_HUMAN (1-724): 0: 1086: 100.00		FGR_HUMAN (363-816): 4.3e-152: 457: 31.29
+	Hs
		411556 HS90B_HUMAN (1-724): 0: 1086: 100.00		LCK_HUMAN (385-817): 4.77e-152: 456: 30.89
+	Hs
		438160 HS90B_HUMAN (1-724): 0: 1086: 100.00		PTK6_HUMAN (396-817): 1.89e-151: 452: 34.78
+	Hs
		411551 HS90A_HUMAN (1-724): 0: 1072: 85.25		LCK_HUMAN (385-817): 4.77e-152: 456: 30.89
+	Hs
		437960 HS90B_HUMAN (1-724): 0: 1086: 100.00		CSK_HUMAN (450-818): 1.85e-141: 427: 37.53
+	Hs
		437965 HS90B_HUMAN (1-724): 0: 1086: 100.00		MATK_HUMAN (409-814): 3.31e-80: 268: 38.86