HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 30711629, 30824926
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024