HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	19394292, 32786267, 34349018
Identification Methods	pull down, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 95
+	Rn
		709238 HS90B_RAT (1-724): 0: 1089: 99.59		SUMO3_RAT (1-94): 2.04e-42: 135: 95.75
+	Hs
		431715 HS90A_HUMAN (1-724): 0: 1072: 85.25		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00
+	Rn
		948937 HS90A_RAT (1-724): 0: 1070: 84.45		SUMO3_RAT (1-94): 2.04e-42: 135: 95.75
+	Hs
		538183 ENPL_HUMAN (3-693): 0: 917: 46.44		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00
+	Sc
		544608 HSC82_YEAST (13-724): 0: 922: 60.22		SMT3_YEAST (3-94): 4.25e-31: 106: 42.39