Protein: 5HT1A
5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)

Gene: 5HT1A, HTR1A
Organism: Homo sapiens
Interactions: 29
UniProt ID: P08908

Gene Ontology (top 5):
GO:0001586 - Gi/o-coupled serotonin receptor activity
GO:0001662 - behavioral fear response
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210434

GPR39
G-protein coupled receptor 39

1

18

Small-scale

0.646

High

477127

S1PR1
Sphingosine 1-phosphate receptor 1

1

19

Small-scale

0.618

High

477128

5HT1D
5-hydroxytryptamine receptor 1D

1

17

Small-scale

0.618

High

477142

GPR26
G-protein coupled receptor 26

1

18

Small-scale

0.618

High

477144

S1PR3
Sphingosine 1-phosphate receptor 3

1

19

Small-scale

0.618

High

477145

MEP50
Methylosome protein WDR77

1

0

Small-scale

0.586

High

477146

COR1C
Coronin-1C

1

0

Small-scale

0.586

High

477123

FGFR1
Fibroblast growth factor receptor 1

1

5

Small-scale

0.582

High

477132

GALR1
Galanin receptor type 1

1

18

Small-scale

0.575

High

477134

SEC13
Protein SEC13 homolog

1

0

Small-scale

0.517

High

131300

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

4

Small-scale

0.479

High

477135

RHOA
Transforming protein RhoA

1

2

Small-scale

0.479

High

477136

EF1A1
Elongation factor 1-alpha 1

1

3

Small-scale

0.479

High

477143

PAWR
PRKC apoptosis WT1 regulator protein

1

2

Small-scale

0.479

High

477131

TGFR2
TGF-beta receptor type-2

1

0

Small-scale

0.458

High

477138

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.458

High

429175

JUN
Transcription factor Jun

1

2

Small-scale

0.437

High

477129

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

2

Small-scale

0.437

High

477133

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

4

Small-scale

0.437

High

477139

MFGM
Lactadherin

1

2

Small-scale

0.437

High

477140

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

3

Small-scale

0.437

High

477141

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

3

Small-scale

0.437

High

477137

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.269

Low

295076

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

Small-scale

0.249

Low

428572

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

477124

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.249

Low

477125

CEBPB
CCAAT/enhancer-binding protein beta

1

0

Small-scale

0.249

Low

477126

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.249

Low

477130

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025