Interactor 1: MMP3 (P08254)
Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)
Gene: MMP3

Interactor 2: PGCA (P16112)
Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) (Chondroitin sulfate proteoglycan 1) [Cleaved into: Aggrecan core protein 2]
Gene: ACAN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19744558
Identification Methods protease assay
Interaction Type protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M10~V-set
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 477
Hs

1 2530
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024