Interactor 1: MMP3 (P08254)
Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)
Gene: MMP3

Interactor 2: MMP14 (P50281)
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)
Gene: MMP14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 8804434
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hemopexin~Hemopexin, Hemopexin~Peptidase_M10, Hemopexin~PG_binding_1, Peptidase_M10~Peptidase_M10, PG_binding_1~Peptidase_M10, PG_binding_1~PG_binding_1
Common GO terms GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
and 7 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 477
Hs

1 582
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024